42922-08-7

Basic information

• Product Name: 1-ETHYL-2-METHYLQUINOLINIUM
• Synonyms: 1-ETHYL-2-METHYLQUINOLINIUM;1-Ethyl-2-methylquinolin-1-ium
• CAS NO: 42922-08-7
• Molecular Formula: C12H14N+
• Molecular Weight: 172.25
• Mol File: 42922-08-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-ETHYL-2-METHYLQUINOLINIUM(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ETHYL-2-METHYLQUINOLINIUM(42922-08-7)
• EPA Substance Registry System: 1-ETHYL-2-METHYLQUINOLINIUM(42922-08-7)

Safety Data

• Hazardous Substances Data: 42922-08-7(Hazardous Substances Data)

Upstream product

• 91-63-4 2-methylquinoline 
• 75-03-6 ethyl iodide 

Relevant articles and documents

Aggregation-induced emission fluorescent probe for detecting aminopeptidase N and preparation of aggregation-induced emission fluorescent probe

The invention discloses an aggregation-induced emission fluorescent probe for detecting aminopeptidase N and a preparation method of the aggregation-induced emission fluorescent probe. The structure of a probe compound is shown as a formula I in the specification. The probe molecule is composed of three main parts: a quinoline-malononitrile-based aggregation-induced emission fluorophore, a self-cleavable linking group and an aminopeptidase N (APN) specific recognition group. When the N-terminal alanyl site of the probe compound is accurately hydrolyzed into amino by APN, the exposed amino is used as an electron donating group, and the electron push-pull effect of a conjugated system is promoted, so that the fluorescence is enhanced. The probe has the advantages that the response speed is high, the sensitivity is high, the Stokes shift is large, the emission wavelength is long, when the concentration of a solution is higher, the fluorescence emission is stronger, and the problem of aggregation-induced fluorescence quenching is effectively avoided.

AIE nano-probe responsive to sulfatase and preparation method and application of AIE nano-probe

The invention discloses a sulfatase-responsive AIE nanoprobe and a preparation method and application thereof. The structural formula of the probe is shown as a formula I in the specification. The probe provided by the invention is a nano probe with an AIE signal amplification function for monitoring sulfatase, and takes a hydrophobic quinoline-malononitrile (DQM) derivative as a core and a hydrophilic sulfate bond as a response group of sulfatase. The probe is simple and easy to prepare and convenient to use, sulfatase can be rapidly detected from fluorescence intensity changes before and after response, and the purpose of rapid detection is achieved. The probe has the characteristics that the probe has no fluorescence, but can generate obvious fluorescence signal enhancement after rapidly reacting with sulfatase, so selective rapid detection of sulfatase is realized. Therefore, the probe disclosed by the invention can be used as an effective tool for detecting sulfatase in tumors, and has the potential of being applied to tumor diagnosis as an inhalation contrast agent.