431-71-0

Basic information

• Product Name: pentafluoroacetone
• Synonyms: pentafluoroacetone;1,1,1,3,3-Pentafluoro-2-propanone;1,1,1,3,3-pentafluoroacetone;1,1,1,3,3-pentafluoropropan-2-one
• CAS NO: 431-71-0
• Molecular Formula: C₃HF₅O
• Molecular Weight: 148.031456
• EINECS: 207-077-1
• Mol File: 431-71-0.mol

Chemical Properties

• Boiling Point: 27.2°C at 760 mmHg
• Appearance: /
• Density: 1.439g/cm³
• Vapor Pressure: 699mmHg at 25°C
• Refractive Index: 1.257
• CAS DataBase Reference: pentafluoroacetone(CAS DataBase Reference)
• NIST Chemistry Reference: pentafluoroacetone(431-71-0)
• EPA Substance Registry System: pentafluoroacetone(431-71-0)

Safety Data

• Hazardous Substances Data: 431-71-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C3HF5O/c4-2(5)1(9)3(6,7)8/h2H

Upstream product

• 381-72-6 difluoroacetyl chloride 
• 334-98-5 (trifluoro methyl) magnesiumiodide 
• 359-78-4 ethyl pentafluoroacetoacetate 
• 79-53-8 chloropentafluoroacetone 
• 85290-62-6 2-phenylamino-1,1,3,3,3-pentafluoropropene 
• 80703-30-6 1-hydrotetrafluoropropan-2-one-1-sulfonyl fluoride 
• 53841-58-0 1,1-difluoro-2-acetoxy-3,3,3-trifluoropropene 
• 75-45-6 Chlorodifluoromethane 
• 75-90-1 2,2,2-Trifluoroacetaldehyde 

Downstream Products

• 67444-74-0 1-[(1-Difluoromethyl-2,2,2-trifluoro-ethoxy)-methoxy-phenyl-methyl]-4-methyl-benzene 
• 67444-58-0 2-difluoromethyl-5-phenyl-5-p-tolyl-2-trifluoromethyl-2,5-dihydro-[1,3,4]oxadiazole 
• 67444-65-9 2-difluoromethyl-5-methyl-5-phenyl-2-trifluoromethyl-2,5-dihydro-[1,3,4]oxadiazole 
• 67444-84-2 [1-(1-Difluoromethyl-2,2,2-trifluoro-ethoxy)-vinyl]-benzene 
• 67444-56-8 2-difluoromethyl-5,5-diphenyl-2-trifluoromethyl-2,5-dihydro-[1,3,4]oxadiazole 
• 129819-16-5 2-n-butyl-4,4-dimethyl-2-phenyloxazolidine 
• 1009-14-9 phenyl butyl ketone 
• 75704-08-4 1-difluoromethyl-1-trifluoromethyl-2-benzofuran-3(1H)-one 
• 90534-16-0 1-(3-thienyl)-1-pentanone 
• 32281-36-0 4,8-dihydrobenzo[1,2-b:4,5-b']dithiophene-4,8-dione 
• 148527-59-7 N,N-diethyl-2-(1,1,1,3,3-pentafluoro-2-hydroxypropan-2-yl)thiophene-3-carboxamide 
• 87337-11-9 2-Difluoromethyl-5,5-diphenyl-2-trifluoromethyl-[1,3]dioxolan-4-one 
• 128038-43-7 syn-pentafluoroacetone anil 
• 460-73-1 1,1,1,3,3-Pentafluoropropane 

Relevant articles and documents

Polyfluorinated enol acetates

The synthesis of polyfluorinated enol acetates has been performed by reductive dechlorination of chloropolyfluoroketones with zinc in Ac2O.Under these conditions, hexafluoroacetone is preferably reduced at the carbonyl group. - Key words: polychlorofluoroketones; reductive dehalogenation; polyfluorinated enol acetates; synthesis; reactivity.

METHOD OF MAKING HYDROFLUOROCARBONS

A method of producing hydrofluorocarbons and methods of producing other commercially attractive compounds formed as by-products of hydrofluorocarbon production by using aldehydes as a principal reactant.

Synthesis of functionalized polyfluoroalkyl hypochlorites and fluoroxy compounds and their reactions with some fluoroalkenes

Several new polyfluoroalkyl hypochlorites and fluoroxy compounds containing Cl, H and Br in the alkyl group have been prepared and characterized by 19F NMR, 1H NMR and IR spectroscopies and by their reactions with fluoroalkenes to produce new polyfluoroethers.The novel compounds are prepared by the CsF-catalyzed addition of F2 or ClF to the C=O bond in CF3C(O)CF2Cl, ClCF2C(O)CF2Cl, and their derivatives HCF2C(O)CF3 and HCF2C(O)CF2Cl.Compounds containing an α-CF3 group exhibit enhanced thermal stability.New fluoroxy compounds and hypochlorites have also been prepared from the acid fluorides CF3-CFX-C(O)F (X = Cl, Br), which are obtained by the ring-opening reaction of hexafluoropropene oxide with (CH3)3SiCl, LiBr and (C2H5)3SiBr.These -OX compounds behave similarly to previously known materials with two α-F atoms, decomposing quickly at room temperature to COF2 and haloalkanes.

REDUCTIVE DEFLUORINATION OF HEXAFLUOROACETONE ANIL

Hexafluoroacetone anil smoothly adds methyllithium at the C=N bond but undergoes reductive defluorination upon the action of Grignard reagents or metallic zinc to give 2-phenylaminopentafluoropropylene.