435345-05-4 Usage
Uses
Used in Organic Synthesis:
(3-Chloro-2-oxo-2H-pyrazin-1-yl)-acetic acid ethyl ester is used as a building block in organic synthesis for the creation of various pharmaceutical and agrochemical products. Its unique structure allows for the development of a range of compounds with different therapeutic and protective properties.
Used in Chemical Research:
In the field of chemical research, (3-Chloro-2-oxo-2H-pyrazin-1-yl)-acetic acid ethyl ester is employed as an intermediate in the production of other chemical compounds. It contributes to the advancement of chemical knowledge and the discovery of new chemical entities.
Used in Drug Development:
(3-Chloro-2-oxo-2H-pyrazin-1-yl)-acetic acid ethyl ester is utilized in the development of new drugs due to its versatile chemical structure. It can be modified and combined with other compounds to create novel pharmaceuticals with potential therapeutic applications.
Used in Crop Protection Product Development:
(3-Chloro-2-oxo-2H-pyrazin-1-yl)-acetic acid ethyl ester is also used in the development of crop protection products, where its chemical properties can be harnessed to create new agents that protect crops from pests and diseases, thereby enhancing agricultural productivity.
Used in Chemical Reactions as a Reagent:
(3-Chloro-2-oxo-2H-pyrazin-1-yl)-acetic acid ethyl ester serves as a reagent in various chemical reactions, facilitating the synthesis of target compounds and contributing to the broader scope of chemical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 435345-05-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,3,5,3,4 and 5 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 435345-05:
(8*4)+(7*3)+(6*5)+(5*3)+(4*4)+(3*5)+(2*0)+(1*5)=134
134 % 10 = 4
So 435345-05-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H9ClN2O3/c1-2-14-6(12)5-11-4-3-10-7(9)8(11)13/h3-4H,2,5H2,1H3
435345-05-4Relevant articles and documents
MASP-2 INHIBITORS AND METHODS OF USE
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Page/Page column 154-155, (2021/06/11)
The present disclosure provides, inter alia, compounds with MASP-2 inhibitory activity, compositions of such compounds, and methods of making and using such compounds.
Development of a scaleable synthesis of a 3-aminopyrazinone acetamide thrombin inhibitor
Ashwood, Michael S.,Alabaster, Ramon J.,Cottrell, Ian F.,Cowden, Cameron J.,Davies, Antony J.,Dolling, Ulf H.,Emerson, Khateeta M.,Gibb, Andrew D.,Hands, David,Wallace, Debra J.,Wilson, Robert D.
, p. 192 - 200 (2013/09/04)
A scaleable route to 2-{3-[(2,2-difluoro-2-(2-pyridyl)ethyl)-animo]-6- chloro-2-oxohydropyrazinyl}-N-(3-fluoro(2-pyridyl))-methyl]acetamide 1 is described in which various scaleup issues were addressed to provide a safe, efficient, and robust route for th
Synthesis of 3-Aminopyrazinone Mediated by 2-Pyridylthioimidate-ZnCl 2 Complexes. Development of an Efficient Route to a Thrombin Inhibitor
Chung, John Y. L.,Cvetovich, Raymond J.,Tsay, Fuh-Rong,Dormer, Peter G.,DiMichele, Lisa,Mathre, David J.,Chilenski, Jennifer R.,Mao, Bing,Wenslow, Robert
, p. 8838 - 8846 (2007/10/03)
A six-step preparation of thrombin inhibitor drug candidate 1 from pyrazinone 7 in 47% overall yield is described. The problem of low reactivity between weak amine nucleophile 4 and poor electrophile 3-bromopyrazinone 17 was overcome with the use of pyrid
