The present invention is directed to compounds represented by Structural Formula (I) and pharmaceutically acceptable salts, solvates and hydrates thereof: (I). The invention is also directed to pharmaceutical compositions, methods of use and methods of making compounds represented by Structural Formula (I) and pharmaceutically acceptable salts, solvates and hydrates thereof.
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(2008/06/13)
Design, synthesis and structure-activity relationship of novel RXR-selective modulators
The synthesis and in vitro characterization of novel RXR-selective ligands possessing various substituted 1-benzofuran or 1-benzothiophene moieties are described.
Michellys, Pierre-Yves,D'Arrigo, Jennifer,Grese, Timothy A.,Karanewsky, Donald S.,Leibowitz, Mark D.,Mais, Dale A.,Mapes, Christopher M.,Reifel-Miller, Anne,Rungta, Deepa,Boehm, Marcus F.
p. 1593 - 1598
(2007/10/03)
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