Total synthesis of (±)-hirsutine: Application of phosphine-catalyzed imine-allene [4 + 2] annulation
The total synthesis of the indole alkaloid hirsutine has been achieved, with a key step being the application of our phosphine-catalyzed [4 + 2] annulation of an imine with ethyl α-methylallenoate. From commercially available indole-2-carboxaldehyde, the target was synthesized in 14 steps and 6.7% overall yield.
Villa, Reymundo A.,Xu, Qihai,Kwon, Ohyun
p. 4634 - 4637
(2012/10/30)
Preparation of (±)-hirsutine and (±)-3-isocorynantheidine
Preparation of indole alkaloids (±)-hirsutine (1) and (±)-3- isocorynantheidine (2) is described.
Stereoselective Total Synthesis of (+/-)-Hirsutine and Related Corynanthe Alkaloids
In a completely stereoselective sequence, an analogue of dihydrosecologanin aglucone has been synthesised via a novel cyclopentenedione dimer and converted into tetracyclic indole alkaloids.
Brown, Richard T.,Jones, Martin F.,Wingfield, Mark
p. 847 - 848
(2007/10/02)
Short syntheses of hirsutine and geissoschizine
-
Wenkert,Vankar,Yadav
p. 7971 - 7972
(2007/10/02)
Transformation of indole alkaloids. I. Conversion of oxindole alkaloids into indole alkaloids
-
Aimi,Yamanaka,Endo,et al.
p. 2015 - 2021
(2007/10/04)
Synthesis of /-/corynantheidine.
-
Szantay,Barczai-Beke
p. 1405 - 1407
(2007/10/08)
More Articles about upstream products of 4684-43-9