473269-70-4

Basic information

• Product Name: 4-tert-Butyl-2,6-diaminoanisole
• Synonyms: 4-TERT-BUTYL-2 6-DIAMINOANISOLE 97;4-t-Butyl-2,6-diaminoanisole;4-tert-butyl-2,6-diamino-1-methoxybenzene;4-TERT-BUTYL-2,6-DIAMINOANISOLE-METHOXYBENZENE-1,3-DIAMINE,95%;4-tert-Butyl-2,6-diaminoanisole;5-(Tert-butyl)-2-Methoxybenzene-1,3-diaMine;2-Methoxy-5-tert-butylbenzene-1,3-diaMine
• CAS NO: 473269-70-4
• Molecular Formula: C₁₁H₁₈N₂O
• Molecular Weight: 194.27
• Mol File: 473269-70-4.mol

Chemical Properties

• Melting Point: 111-113 °C(lit.)
• Boiling Point: 329.9 °C at 760 mmHg
• Flash Point: 161.1 °C
• Appearance: White to orange/Powder
• Density: 1.051 g/cm³
• Vapor Pressure: 0.000172mmHg at 25°C
• Refractive Index: 1.56
• CAS DataBase Reference: 4-tert-Butyl-2,6-diaminoanisole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-tert-Butyl-2,6-diaminoanisole(473269-70-4)
• EPA Substance Registry System: 4-tert-Butyl-2,6-diaminoanisole(473269-70-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 473269-70-4(Hazardous Substances Data)

Usage

Uses

Used in Cosmetic Industry:
4-tert-Butyl-2,6-diaminoanisole is used as a hair dye ingredient for its efficient oxidation and coupling abilities, which contribute to the coloration and stability of hair dyes. Its complex chemical structure allows for versatile applications in hair color products, enhancing their performance and effectiveness.
Used in Hair Dye Products:
4-tert-Butyl-2,6-diaminoanisole is used as a key component in hair dye formulations for its ability to facilitate the oxidation and coupling processes that are essential for achieving the desired hair color. Its presence in these products helps to ensure a long-lasting and vibrant color result.
However, it is important to note that due to its potential health risks, such as skin sensitization and eye and skin irritation, 4-tert-Butyl-2,6-diaminoanisole should always be used under proper safety precautions to minimize the risk of adverse effects. This may include the use of protective gloves, eye protection, and ensuring adequate ventilation during application. Additionally, it is crucial to follow the manufacturer's instructions and guidelines for safe use and handling of products containing 4-tert-Butyl-2,6-diaminoanisole.

InChI:InChI=1/C11H18N2O/c1-11(2,3)7-5-8(12)10(14-4)9(13)6-7/h5-6H,12-13H2,1-4H3

Upstream product

• 77055-30-2 5-tert-butyl-2-methoxy-1,3-dinitrobenzene 

Downstream Products

• 404010-35-1 N-(3-amino-5-tert-butyl-2-methoxy-phenyl)-methanesulfonamide 
• 848149-05-3 C₂₉H₃₅N₃O₅ 
• 1379594-80-5 C₁₉H₂₆N₂O₇ 
• 854669-22-0 N,N'-bis(3-bromo-5-tert-butyl-2-methoxyphenyl)-5-tert-butyl-2-methoxy-1,3-phenylenediamine 
• 1041862-64-9 N,N'-bis[3-(3-bromo-5-tert-butyl-2-methoxyanilino)-5-tert-butyl-2-methoxyphenyl]-5-tert-butyl-2-methoxy-1,3-phenylenediamine 

Relevant articles and documents

7-(Piperazine-1-Ymethyl)-1H-Indole-2-Carboxylic Acid (Phenyl)-Amide Derivatives and Allied Compounds as P38 Map Kinase Inhibitors for the Treatment of Respiratory Diseases

The present invention provides compounds according to general formula (I) which are proposed for the treatment of respiratory complaints, particularly asthma and COPD.

Discovery and optimization of p38 inhibitors via computer-assisted drug design

Integration of computational methods, X-ray crystallography, and structure-activity relationships will be disclosed, which lead to a new class of p38 inhibitors that bind to p38 MAP kinase in a Phe out conformation.

Bis-Amination of Aryl Halides

Disclosed are methods for making 1,3- and 1,4-diamino-phenyl intermediates by utilizing bis-amination of ortho-substituted aryl halides.

1,4-Disubstituted benzo-fused compounds

Disclosed are novel 1,4-disubstituted benzo-fused compounds wherein G, X, L, Q, n and Y are defined herein. The compounds are useful in pharmaceutic compositions for treating diseases or pathological conditions involving inflammation such as chronic infla