473780-80-2

Basic information

• Product Name: 5,5-dimethyl-3-(3-triethoxysilylpropyl)imidazolidine-2,4-dione
• CAS NO: 473780-80-2
• Molecular Formula: C₁₄H₂₈N₂O₅Si
• Molecular Weight: 332.47
• Mol File: 473780-80-2.mol

Chemical Properties

• Density: 1.054g/cm³
• Refractive Index: 1.458
• CAS DataBase Reference: 5,5-dimethyl-3-(3-triethoxysilylpropyl)imidazolidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5,5-dimethyl-3-(3-triethoxysilylpropyl)imidazolidine-2,4-dione(473780-80-2)
• EPA Substance Registry System: 5,5-dimethyl-3-(3-triethoxysilylpropyl)imidazolidine-2,4-dione(473780-80-2)

Safety Data

• Hazardous Substances Data: 473780-80-2(Hazardous Substances Data)

Upstream product

• 5089-70-3 (3-chloropropyl)triethoxysilane 
• 77-71-4 5,5-dimethyl-imidazolidine-2,4-dione 

Relevant articles and documents

PHB/PCL fibrous membranes modified with SiO2?TiO2-based core?shell composite nanoparticles for hydrophobic and antibacterial applications

In order to prepare multifunctional fibrous membranes with hydrophobicity, antibacterial properties and UV resistance, we used silica and titanium dioxide for preparing SiO2?TiO2 nanoparticles (SiO2?TiO2 NPs) to create roughness on the fibrous membranes surfaces. The introduction of TiO2 was used for improving UV resistance. N-Halamine precursor and silane precursor were introduced to modify SiO2?TiO2 NPs to synthesize SiO2?TiO2-based core?shell composite nanoparticles. The hydrophobic antibacterial fibrous membranes were prepared by a dip-pad process of electrospun biodegradable polyhydroxybutyrate/poly-?-caprolactone (PHB/PCL) with the synthesized SiO2?TiO2-based core?shell composite nanoparticles. TEM, SEM and FT-IR were used to characterize the synthesized SiO2?TiO2-based core?shell composite nanoparticles and the hydrophobic antibacterial fibrous membranes. The fibrous membranes not only showed excellent hydrophobicity with an average water contact angle of 144° ± 1°, but also appreciable air permeability. The chlorinated fibrous membranes could inactivate all S. aureus and E. coli O157:H7 after 5 min and 60 min of contact, respectively. In addition, the chlorinated fibrous membranes exhibited outstanding cell compatibility with 102.1% of cell viability. Therefore, the prepared hydrophobic antibacterial degradable fibrous membranes may have great potential application for packaging materials.

N-halamine biocidal materials with superior antimicrobial efficacies for wound dressings

This work demonstrated the successful application of N-halamine technology for wound dressings rendered antimicrobial by facile and inexpensive processes. Four N-halamine compounds, which possess different functional groups and chemistry, were synthesized. The N-halamine compounds, which contained oxidative chlorine, the source of antimicrobial activity, were impregnated into or coated onto standard non-antimicrobial wound dressings. N-halamine-employed wound dressings inactivated about 6 to 7 logs of Staphylococcus aureus and Pseudomonas aeruginosa bacteria in brief periods of contact time. Moreover, the N-halamine-modified wound dressings showed superior antimicrobial efficacies when compared to commercially available silver wound dressings. Zone of inhibition tests revealed that there was no significant leaching of the oxidative chlorine from the materials, and inactivation of bacteria occurred by direct contact. Shelf life stability tests showed that the dressings were stable to loss of oxidative chlorine when they were stored for 6 months in dark environmental conditions. They also remained stable under florescent lighting for up to 2 months of storage. They could be stored in opaque packaging to improve their shelf life stabilities. In vitro skin irritation testing was performed using a three-dimensional human reconstructed tissue model (EpiDerm). No potential skin irritation was observed. In vitro cytocompatibility was also evaluated. These results indicate that N-halamine wound dressings potentially can be employed to prevent infections, while at the same time improving the healing process by eliminating undesired bacterial growth.

Method for Attachment of Silicon-Containing Compounds to a Surface and for Synthesis of Hypervalent Silicon-Compounds

A method for inducing a hypervalent state within silicon-containing compounds by which they can be chemically attached to a surface or substrate and/or organized onto a surface of a substrate. The compounds when attached to or organized on the surface may have different physical and/or chemical properties compared to the starting materials.

N-HALAMINE SILOXANES FOR USE IN BIOCIDAL COATINGS AND MATERIALS

Heterocyclic and acyclic silane monomers and siloxane polymers, and their halogenated derivatives, are provided for the purpose of functionalizing surfaces or materials so as to render them biocidal upon exposure to oxidative halogen solutions.The biocidal function can be imparted either before or after bonding or adhesion to the surface or material. The biocidal surfaces and materials can then be used to inactivate pathogenic microorganisms such as bacteria, fungi, and yeasts, as well as virus particles, which can cause infectious diseases, and those microorganisms which cause noxious odors and unpleasant coloring such as mildew. Examples of surfaces and materials which can be rendered biocidal in this invention include, but are not limited to, cellulose, chitin, chitosan, synthetic fibers, glass, ceramics, plastics, rubber, cement grout, latex caulk, porcelain, acrylic films, vinyl, polyurethanes, silicon tubing, marble, metals, metal oxides, and silica.