478149-00-7

Basic information

• Product Name: Thieno[2,3-c]pyridine-2-carboxylic acid (9CI)
• Synonyms: Thieno[2,3-c]pyridine-2-carboxylic acid (9CI);thieno[2,3-c]pyridine-2-carboxylic acid
• CAS NO: 478149-00-7
• Molecular Formula: C₈H₅NO₂S
• Molecular Weight: 179.1958
• Product Categories: THIENOPYRIDINE
• Mol File: 478149-00-7.mol

Chemical Properties

• Boiling Point: 418.262°C at 760 mmHg
• Flash Point: 206.758°C
• Appearance: /
• Density: 1.509g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.732
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: Thieno[2,3-c]pyridine-2-carboxylic acid (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Thieno[2,3-c]pyridine-2-carboxylic acid (9CI)(478149-00-7)
• EPA Substance Registry System: Thieno[2,3-c]pyridine-2-carboxylic acid (9CI)(478149-00-7)

Safety Data

• Hazardous Substances Data: 478149-00-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Thieno[2,3-c]pyridine-2-carboxylic acid (9CI) is used as a key building block for the synthesis of various bioactive molecules, particularly in the development of inhibitors such as BET bromodomain inhibitors. These inhibitors play a crucial role in modulating the activity of specific protein targets, which can be beneficial in the treatment of various diseases, including cancer and inflammatory disorders.
In the preparation of BET bromodomain inhibitors, Thieno[2,3-c]pyridine-2-carboxylic acid (9CI) serves as a valuable component due to its ability to interact with the target protein's active site, thereby disrupting its function and potentially leading to therapeutic benefits. The development of such inhibitors can be a promising approach in the treatment of diseases where the targeted proteins play a significant role in their progression.

InChI:InChI=1/C8H5NO2S/c10-8(11)6-3-5-1-2-9-4-7(5)12-6/h1-4H,(H,10,11)

Upstream product

• 870243-58-6 methyl thieno[2,3-c]pyridine-2-carboxylate 
• 145325-40-2 4-bromo-thieno<2,3-c>pyridine-2-carboxylic acid methyl ester 
• 70201-42-2 3,5-dibromopyridine-4-carboxaldehyde 
• 625-92-3 3,5-dibromopyridine 
• 478148-99-1 ethyl thieno[2,3-c]pyridine-2-carboxylate 

Downstream Products

• 1453173-71-1 thieno[2,3-c]pyridine-2-carboxylic acid 4-(morpholine-4-sulfonyl)-benzylamide 
• 1362142-24-2 N-{[4-(3,5-difluorobenzenesulfonyl)phenyl]methyl}thieno[2,3-c]pyridine-2-carboxamide 

Relevant articles and documents

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