- NON-SYSTEMIC TGR5 AGONISTS
-
Compounds of structure (I), or a stereoisomer, tautomer, pharmaceutically acceptable salt or prodrug thereof, wherein R1, R2, R3, R4, R8, R9, R10, R11, R12, A1, A2, X, Y and Z are as defined herein. Uses of such compounds as TGR5 antagonists and for treatment of various indications, including Type II diabetes meletus are also provided.
- -
-
Page/Page column 226
(2013/07/05)
-
- Process for preparation of 2-methoxy-3,6-dichloro-benzoic acid
-
An improved method of preparing 2-methoxy-3,6-dichloro-benzoic acid which comprises the step of oxidizing 2-methoxy-3,6-dichloro-benzyl alcohol into the correspondingly substituted benzoic acid, where the improvement resides in that the said benzyl alcoho
- -
-
-
- Process for preparation of 2-methoxy-3,6-dichloro-benzoic acid
-
An improved method of preparing 2-methoxy-3,6-dichloro-benzoic acid which comprises the step of oxidizing 2-methoxy-3,6-dichloro-benzyl alcohol into the correspondingly substituted benzoic acid, where the improvement resides in that the said benzyl alcoho
- -
-
-