49775-37-3Relevant articles and documents
Method for preparing aqueous composition for sterilization
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Page/Page column 13, (2008/06/13)
A method for preparing an aqueous composition for sterilization, which comprises the step of mixing an acylimidazole represented by the general formula (II): wherein R represents a substituted or unsubstituted C1-C20 alkyl group, or a substituted or unsubstituted C6-C30 aryl group, with an aqueous solution containing a hydrogen peroxide source to produce a corresponding peroxycarboxylic acid. An aqueous composition for sterilization suitable for sterilization of medical apparatuses such as endoscopes, which can be safely and quickly prepared upon use, and a method for preparing the same are provided.
Alkoxy-acyl carnitines and pharmaceutical compositions containing same
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, (2008/06/13)
A novel class of alkoxy-acyl carnitines, wherein the alkoxy-acyl radical has from 4 to 6 carbon atoms (tipically: methoxypropionyl, ethoxypropionyl and propoxyacetyl) is prepared by reacting a solution of a carnitine salt in an organic solvent with an alkoxy-acyl halogenide, thus obtaining the corresponding salt of alkoxy-acyl carnitine. By eluting an aqueous solution of this salt through a column of an ion exchange resin activated in Cl- or Br- form, the chloride or bromide of alkoxy-acyl carnitine is obtained. The alkoxy-acyl carnitines are therapeutically effective in the treatment of cardiac disorders, hyperlipidaemias and hyperlipoproteinaemias.
Esters of alkoxy-acylderivatives of carnitine and pharmaceutical compositions containing same
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, (2008/06/13)
A novel class of esters of alkoxy-acylderivatives of carnitine, wherein the alkoxy-acyl radical has from 3 to 6 carbon atoms (typically: methoxyacetyl, methoxypropionyl, ethoxyacetyl, ethoxypropionyl and propoxyacetyl) is prepared by esterifying carnitine and then acylating the carnitine ester. Such esters are therapeutically useful in the treatment of cardiac disorders, hyperlipidaemias and hyperlipoproteinaemias.