60044-74-8

Basic information

• Product Name: 4-ETHOXY-2-BUTANONE
• Synonyms: 4-ETHOXY-2-BUTANONE;4-ETHOXY-2-BUTANONE 90+%;2-Butanone, 4-ethoxy- (6CI,7CI,9CI)
• CAS NO: 60044-74-8
• Molecular Formula: C₆H₁₂O₂
• Molecular Weight: 116.16
• Product Categories: ACETYLGROUP
• Mol File: 60044-74-8.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 153°C
• Flash Point: 39.6°C
• Appearance: /
• Density: 0,92 g/cm3
• Vapor Pressure: 3.72mmHg at 25°C
• Refractive Index: 1.4060-1.4100
• CAS DataBase Reference: 4-ETHOXY-2-BUTANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ETHOXY-2-BUTANONE(60044-74-8)
• EPA Substance Registry System: 4-ETHOXY-2-BUTANONE(60044-74-8)

Safety Data

• Statements: 10
• Safety Statements: 16
• RIDADR: 1224
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 60044-74-8(Hazardous Substances Data)

Usage

General Description

4-Ethoxy-2-butanone, also known as ethyl 4-ethoxybutanoate, is an organic chemical compound with the molecular formula C6H12O2. It is a colorless liquid with a fruity odor that is commonly used as a solvent in the production of coatings, adhesives, and other industrial applications. 4-Ethoxy-2-butanone also has potential applications in the manufacturing of pharmaceuticals and as a flavoring agent in food products. It is considered to be relatively safe for use, with low toxicity and minimal environmental impact. However, as with any chemical compound, proper handling and storage procedures should be followed to ensure safety and minimize risks.

InChI:InChI=1/C6H12O2/c1-3-8-5-4-6(2)7/h3-5H2,1-2H3

Upstream product

• 24731-39-3 4-(phenylsulfonyl)butan-2-one 
• 763-69-9 ethyl 3-ethoxypropionate 
• 4324-38-3 3-ethoxypropanoic acid 
• 217969-12-5 1,3,3-triethoxy-butane 
• 7647-01-0 hydrogenchloride 
• 10150-87-5 1-acetoxybutan-3-one 
• 64-17-5 ethanol 
• 139571-54-3 1-[2-(2,4-Dimethyl-[1,3]dioxolan-2-yl)-ethoxy]-propan-2-ol 
• 110-87-2 3,4-dihydro-2H-pyran 
• 881421-26-7 (Z)-3-Ethoxy-but-2-en-1-ol 
• 1191-99-7 2,3-dihydro-2H-furan 
• 75-16-1 methylmagnesium bromide 
• 49775-37-3 3-ethoxypropionyl chloride 
• 22409-85-4 4-phenoxybutan-2-one 

Downstream Products

• 78-94-4 methyl vinyl ketone 
• 10252-46-7 3-methyl-1-phenyl-4,5-dihydropyrazole 
• 89975-71-3 1-Propyloxy-butanon-(3) 
• 105338-86-1 4-ethoxy-butan-2-one-(2,4-dinitro-phenylhydrazone) 

Relevant articles and documents

Functionalized α-oximinoketones as building blocks for the construction of imidazoline-based potential chiral auxiliaries

Functionalized α-oximinoketones with β-alkoxy, β-alkyl, and β-sulfenyl groups were used as efficient synthons for the preparation of chiral 1-acyl-4-imidazolin-2-ones and 1-acylimidazolidin-2-ones. For the preparation of the former heterocycles, α-oximinoketones were transformed into their respective imidazole N-oxides by neutral treatment with a chiral triazine, followed by reaction with acetic or propionic anhydrides to furnish the desired chiral 1-acetyl- or 1-propionyl-4-imidazolin-2-ones in moderate overall yields. Upon palladium hydroxide-catalyzed hydrogenation, these series were converted into their corresponding 1-acylimidazolidin-2-ones in high diastereoisomeric ratios. Thus, these novel chiral 1-acetyl- and 1-propionyl-imidazolidin-2-ones were obtained with a variety of alkyl groups at the C-4 and C-5 positions of the heterocycle, through a three-step methodology, and can be applied as new potential chiral auxiliaries.

Acidic ionic liquid [NMP]H2PO4 as dual solvent-catalyst for synthesis of β-alkoxyketones by the oxa-Michael addition reactions

Acidic ionic liquid N-methyl-2-pyrrolidonium dihydrogen phosphate [NMP]H2PO4 was prepared and used as efficient catalyst and reaction medium to synthesize β-alkoxyketones by the oxa-Michael addition reactions for the first time. The

The ionic liquid ethyltri-n-butylphosphonium tosylate as solvent for the acid-catalysed hetero-Michael reaction

A new and convenient method for the acid-catalysed Michael addition reactions of alcohols, thiols and amines to methyl vinyl ketone has been developed using the ionic liquid ethyltri-n-butylphosphonium tosylate. The reaction conditions are mild and obviat