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4-(4-BOC-PIPERAZINO-1-YL)-3-FLUOROBENZALDEHYDE, also known as Boc-Pip-3-fluoro-benzaldehyde, is a chemical compound that serves as a crucial building block in the synthesis of pharmaceuticals and organic compounds. It is recognized for its ability to modulate biological processes and is instrumental in the development of new chemical entities. With its distinctive structure and properties, 4-(4-BOC-PIPERAZINO-1-YL)-3-FLUOROBENZALDEHYDE is pivotal in the field of medicinal chemistry, contributing significantly to drug discovery and development.

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  • 501126-37-0 Structure
  • Basic information

    1. Product Name: 4-(4-BOC-PIPERAZINO-1-YL)-3-FLUOROBENZALDEHYDE
    2. Synonyms: 4-(4-BOC-PIPERAZINO-1-YL)-3-FLUOROBENZALDEHYDE
    3. CAS NO:501126-37-0
    4. Molecular Formula: C16H21FN2O3
    5. Molecular Weight: 308.351
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 501126-37-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-(4-BOC-PIPERAZINO-1-YL)-3-FLUOROBENZALDEHYDE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-(4-BOC-PIPERAZINO-1-YL)-3-FLUOROBENZALDEHYDE(501126-37-0)
    11. EPA Substance Registry System: 4-(4-BOC-PIPERAZINO-1-YL)-3-FLUOROBENZALDEHYDE(501126-37-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 501126-37-0(Hazardous Substances Data)

501126-37-0 Usage

Uses

Used in Pharmaceutical Synthesis:
4-(4-BOC-PIPERAZINO-1-YL)-3-FLUOROBENZALDEHYDE is used as a key intermediate for the creation of novel drug candidates. Its unique structure allows it to be a versatile component in the synthesis of various pharmaceuticals, contributing to the development of new treatments for a range of medical conditions.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 4-(4-BOC-PIPERAZINO-1-YL)-3-FLUOROBENZALDEHYDE is utilized as a research tool to explore and understand the interactions between chemical compounds and biological targets. Its role in modulating biological processes makes it valuable for studying the mechanisms of action of potential drugs and advancing the understanding of disease pathways.
Used in Organic Chemistry:
4-(4-BOC-PIPERAZINO-1-YL)-3-FLUOROBENZALDEHYDE is also employed in organic chemistry as a reagent or starting material for the synthesis of complex organic molecules. Its fluorinated and protected amine group provide specific reactivity and selectivity, making it suitable for various organic transformations and the construction of molecular frameworks with potential applications in material science, agrochemistry, and other areas.

Check Digit Verification of cas no

The CAS Registry Mumber 501126-37-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,1,1,2 and 6 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 501126-37:
(8*5)+(7*0)+(6*1)+(5*1)+(4*2)+(3*6)+(2*3)+(1*7)=90
90 % 10 = 0
So 501126-37-0 is a valid CAS Registry Number.

501126-37-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 4-(2-fluoro-4-formylphenyl)piperazine-1-carboxylate

1.2 Other means of identification

Product number -
Other names 4-(4-Boc-piperazine-1-yl)-3-fluorobenzaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:501126-37-0 SDS

501126-37-0Relevant articles and documents

NOVEL COMPOUNDS AS INHIBITORS OF HISTONE DEACETYLASE 6 AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME

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Page/Page column 462; 464; 465, (2022/01/24)

The present invention relates to a new compound having an inhibitory activity of histone deacetylase 6 (HDAC6), stereoisomers thereof, pharmaceutically acceptable salts thereof, a use thereof in the preparation of a drug, a pharmaceutical composition comprising them, a prophylactic or therapeutic method corresponding, and a method of preparing a new derivative 1,3,4-oxadiazole triazol, a novel compound having selective HDAC6 inhibitory activity being represented by the following chemical formula I.

PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR

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Page/Page column 94, (2009/07/18)

The present invention is directed to piperidinyl and piperazinyl derivatives of formula (I) useful as inhibitors of the NPY Y2 receptor, pharmaceutical compositions comprising said compounds, processes for the preparation of said compounds and the use of

Pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists

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Page/Page column 26, (2008/06/13)

Compounds having the structural formula I or a pharmaceutically acceptable salt thereof, wherein R is optionally substituted phenyl, furanyl, thienyl, pyridyl, pyridyl N-oxide, oxazolyl or pyrrolyl, or cycloalkenyl R1, R2, R3, R4 and R5 are H, alkyl or alkoxyalkyl; and Z is optionally substituted aryl or heteroaryl are disclosed. Also disclosed is the use of compounds of formula I in the treatment of central nervous system diseases, in particular Parkinson's disease, alone or in combination with other agents for treating Parkinson's disease, and pharmaceutical compositions comprising them.

2-Alkynyl-and 2-alkenyl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists

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Page 26, (2008/06/13)

Compounds having the structural formula I or a pharmaceutically acceptable salt thereof, wherein R is R1, R2, R3, R4 and R5 are H, alkyl or alkoxyalkyl; R6 is H, alkyl, hydroxyalkyl or —CH2F; R7, R8 and R9 are H, alkyl, alkoxy, alkylthio, alkoxyalkyl, halo or —CF3; and Z is optionally substituted aryl, heteroaryl or heteroaryl-alkyl are disclosed. Also disclosed is the use of compounds of formula I in the treatment of central nervous system diseases, in particular Parkinson's disease, alone or in combination with other agents for treating Parkinson's disease, and pharmaceutical compositions comprising them.

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