- Synthesis of vicinal diamino-endo, cis-norbornene derivatives
-
The synthesis of 2,3-disubstituted-endo,cis-norborn-5-ene derivatives is described. Cyclic ureas and cis vicinal diamines substituted with p-tolyl and perfluorophenyl rings were prepared. The use of potassium carbonate as an innocuous CO source for the formation of a cyclic urea was demonstrated. Copyright Taylor & Francis Group, LLC.
- Hossain, Delwar,Lavoie, Gino G.
-
experimental part
p. 1200 - 1210
(2012/04/10)
-
- An NMR study of sequential intermediates and collateral products in the conversion of 1,3,6,8-tetraazatricyclo[4.4.1.13,8]dodecane (TATD) to 1,3,6,8-tetraazatricyclo[4.3.1.13,8]undecane (TATU)
-
In situ 1H nuclear magnetic resonance spectroscopy was used to investigate the processes that occur during the synthesis of 1,3,6,8-tetraazatricyclo[4.3.1.13,8]undecane (TATU). NMR analysis showed a reaction mixture containing more than one compound. The production of these intermediates and collateral products was rationally supported by a careful 1H NMR monitoring study. We characterized 1,3,5-triazabicyclo[3.2.1]octane (TABO, 4) and 3-(2-aminoethyl)-1,3,5-triazabicyclo[3.2.1]octane (AETABO, 7) by 1H and 13C NMR in D2O solution inside the NMR sample tube, as an intermediate and collateral product of the reaction, respectively. Further, a reaction of 1,3,6,8-tetraazatricyclo[4.4.1.13,8]dodecane (TATD) with 15N-labeled ammonium chloride was carried out. The 15N NMR and GC-MS experiments indicated that 15N was incorporated into TATU, TABO, and urotropine.
- Rivera, Augusto,Nú?ez, Martín E.,Avella, Eliseo,Ríos-Motta, Jaime
-
p. 2154 - 2158
(2008/09/20)
-
- METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS
-
A method for repelling arthropods involving treating an object or area with an arthropod repelling effective amount of at least one compound having the formula wherein X is O, S, NH, N-NH2, N-CH3 or CH2, R' is H or alkyl, R" is alkyl, n is 0, 1, 2, 3 or 4, and mixtures thereof, optionally including a earner material or earner. The compound is preferably selected from homopiperazine, 1-methylhomopiperazine, 1-methylpyrrolidine, (R)- (-)-2-methylpiperazine, (S)-(+)-2-methylpiperazine, 2-methylpiperazine, 1 -methylpiperazine, pyrrolidine, 1-methylpiperidine, piperidine, 1-ethylpiperazine, 1-methylimidazolidine, 1- methylthiomorpholine, 1,4-dimethylpiperazine, homopiperidine, imidazolidine, 4- methylpiperidine, thiomoφholine, l-amino-4-methylpiperazine, 4-methylmoipholine, azocane, 2,6-dimethylpiperazine, 2,5-dimethylpiperazine, piperazine, 1-methylhomopiperidine, or mixtures thereof.
- -
-
Page/Page column 25
(2008/12/07)
-
- N,N'-bisacylimidazolidines from 1,2-diamines
-
A variety of novel 1,3-bisacylimidazolidines were prepared in a one-pot procedure from 1,2-diamines. Condensation of 1,2-diaminoethane or a selection of chiral 1,2-diamines with a variety of aldehydes under dehydrating conditions gives rise to 1,3-bisunsubstituted imidazolidines. These imidazolidines were not isolated, but were treated with acid chlorides or anhydrides to give the novel 1,3-bisacylimidazolidines.
- Coldham,Houdayer,Judkins,Witty
-
p. 1463 - 1466
(2007/10/03)
-
- Acyl Derivatives of Cyclic Secondary Amines. Part 1. Dipole Stabilization of Anions: the Cumulative effect of Two Stabilizing Groups
-
Lithiation studies with diacylimidazolidines, diacylhexahydropyrimidines, and triacylhexahydro-1,3,5-triazines indicate that no substantial increase in carbanion stability occurs as a result of the introduction of the second stabilizing group.Relative energies are calculated for three conformers of lithiated diformylimidazolidine, six conformers of lithiated diformylhexahydropyrimidine, and eight conformers of lithiated triformylhexahydro-sym-triazine.For the six-membered rings, conformers with equatorial lithium are always more stable those those with axial lithium.Although equatorial syn-syn conformers (with double O-Li co-ordination) are more stable than equatorial syn-anti, the difference is significantly less than that found between the corresponding syn-anti and (least stable) anti-anti conformers.
- Katritzky, Alan R.,Murugan, Ramiah,Luce, Hudson,Zerner, Michael,Ford, George P.
-
p. 1695 - 1700
(2007/10/02)
-
- 2-Imino-imidazolidine derivatives
-
2-Imino-imidazolidine derivatives of the formula STR1 wherein R1, R2, R3 and R4 are as hereinafter set forth, and pharmaceutically acceptable acid addition salts thereof, are described. The 2-imino-imidazolidine derivatives are useful in the treatment of hypertension.
- -
-
-
