510729-27-8 Usage
Uses
Used in Pharmaceutical Industry:
4-tert-Butoxycarbonylaminobut-2-enoic Acid Ethyl Ester is used as a synthetic intermediate for the production of 3,4-disubstituted pyrroles, which are important building blocks in the synthesis of various pharmaceutical compounds. These pyrroles have potential applications as therapeutic agents, with potential uses in the treatment of various diseases and disorders.
Used in Organic Synthesis:
In the field of organic synthesis, 4-tert-Butoxycarbonylaminobut-2-enoic Acid Ethyl Ester is used as a versatile intermediate for the preparation of a wide range of organic compounds. Its unique chemical structure allows for various synthetic transformations, making it a valuable tool for the synthesis of complex organic molecules.
Used in Research and Development:
4-tert-Butoxycarbonylaminobut-2-enoic Acid Ethyl Ester is also used in research and development settings, where it can be employed as a starting material for the synthesis of novel compounds with potential applications in various fields, such as materials science, pharmaceuticals, and agrochemicals. Its unique properties and reactivity make it an attractive candidate for the development of new synthetic methods and strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 510729-27-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,1,0,7,2 and 9 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 510729-27:
(8*5)+(7*1)+(6*0)+(5*7)+(4*2)+(3*9)+(2*2)+(1*7)=128
128 % 10 = 8
So 510729-27-8 is a valid CAS Registry Number.
510729-27-8Relevant articles and documents
Efficient Synthesis of (-)-Hanishin, (-)-Longamide B, and (-)-Longamide B Methyl Ester through Piperazinone Formation from 1,2-Cyclic Sulfamidates
Shiokawa, Zenyu,Inuki, Shinsuke,Fukase, Koichi,Fujimoto, Yukari
, p. 616 - 620 (2016)
We describe a simple chiral-pool synthesis of (-)-longamide B, (-)-longamide B methyl ester, and (-)-hanishin. The key feature of the total synthesis is the formation of a piperazinone from a 1,2-cyclic sulfamidate and methyl 2-pyrrolecarboxylate, which permits efficient construction of the pyrrolopiperazinone core scaffold.
Live-cell imaging and profiling of c-Jun N-terminal kinases using covalent inhibitor-derived probes
Qian, Linghui,Pan, Sijun,Lee, Jun-Seok,Ge, Jingyan,Li, Lin,Yao, Shao Q.
supporting information, p. 1092 - 1095 (2019/01/29)
c-Jun N-terminal kinases (JNKs) are involved in critical cellular functions. Herein, small-molecule JNK-targeting probes are reported based on a covalent inhibitor. Together with newly developed two-photon fluorescence Turn-ON reporters and chemoproteomic studies, we showed that some probes may be suitable for live-cell imaging and profiling of JNKs.
Synthesis of polysubstituted pyrroles
Poulard, Celine,Cornet, Julien,Legoupy, Stephanie,Dujardin, Gilles,Dhal, Robert,Huet, Francois
experimental part, p. 359 - 361 (2010/04/23)
Cross coupling metathesis reactions from two ethylenic compounds 4 and 5 easily led to Michael acceptors 6ab and 7a-b. Reaction of these compounds, or of enone 5', with p-toluenesulfonylmethyl isocyanide (TosMIC) provided the disubstituted pyrroles 9a-c a
