51857-11-5

Basic information

• Product Name: 7-O-methyleriodictyol
• Synonyms: 7-O-methyleriodictyol;Eriodictyol 7-methyl ether;Sternbin
• CAS NO: 51857-11-5
• Molecular Formula: C₁₆H₁₄O₆
• Molecular Weight: 302.27876
• Mol File: 51857-11-5.mol

Chemical Properties

• Melting Point: 215 °C
• Boiling Point: 607.2°Cat760mmHg
• Flash Point: 231.3°C
• Appearance: /
• Density: 1.458g/cm³
• Vapor Pressure: 2.45E-15mmHg at 25°C
• Refractive Index: 1.664
• PKA: 7.39±0.40(Predicted)
• CAS DataBase Reference: 7-O-methyleriodictyol(CAS DataBase Reference)
• NIST Chemistry Reference: 7-O-methyleriodictyol(51857-11-5)
• EPA Substance Registry System: 7-O-methyleriodictyol(51857-11-5)

Safety Data

• Hazardous Substances Data: 51857-11-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Applications:
7-O-methyleriodictyol is used as a therapeutic agent for its potential antioxidant and anti-inflammatory properties, which can help in managing various inflammatory conditions and oxidative stress-related disorders.
Used in Nutraceutical Applications:
7-O-methyleriodictyol is used as a dietary supplement for its health-promoting effects, including its potential to support immune function and overall well-being.
Used in Cancer Prevention:
7-O-methyleriodictyol is used as a chemopreventive agent for its potential to inhibit the development of cancer by reducing oxidative stress and inflammation, which are known risk factors for the disease.
Used in Cancer Treatment:
7-O-methyleriodictyol is used as a chemotherapeutic agent for its potential to target cancer cells and inhibit their growth and proliferation, offering a novel approach to cancer treatment.
Used in Research:
7-O-methyleriodictyol is used as a subject of scientific investigation to further understand its mechanisms of action, potential therapeutic benefits, and possible applications in various medical fields.

InChI:InChI=1/C16H14O6/c1-21-9-5-12(19)16-13(20)7-14(22-15(16)6-9)8-2-3-10(17)11(18)4-8/h2-6,14,17-19H,7H2,1H3/t14-/m0/s1

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Relevant articles and documents

Sterubin: Enantioresolution and Configurational Stability, Enantiomeric Purity in Nature, and Neuroprotective Activity in Vitro and in Vivo

Alzheimer′s disease (AD) is a neurological disorder with still no preventive or curative treatment. Flavonoids are phytochemicals with potential therapeutic value. Previous studies described the flavanone sterubin isolated from the Californian plant Eriodictyon californicum as a potent neuroprotectant in several in vitro assays. Herein, the resolution of synthetic racemic sterubin (1) into its two enantiomers, (R)-1 and (S)-1, is described, which has been performed on a chiral chromatographic phase, and their stereochemical assignment online by HPLC-ECD coupling. (R)-1 and (S)-1 showed comparable neuroprotection in vitro with no significant differences. While the pure stereoisomers were configurationally stable in methanol, fast racemization was observed in the presence of culture medium. We also established the occurrence of extracted sterubin as its pure (S)-enantiomer. Moreover, the activity of sterubin (1) was investigated for the first time in vivo, in an AD mouse model. Sterubin (1) showed a significant positive impact on short- and long-term memory at low dosages.