Metal-free hydration of ynamides: Convenient approach to amides
The trifluoroacetic acid (TFA) mediated hydration of ynamides was developed, which is an efficient approach for the synthesis of N-monosubstituted amides. This convenient method is effective with a wide range of substrates under room temperature condition, and the products are obtained in high to excellent yields through an easy work-up process.
Amide bond formation via C(sp3)-H bond functionalization and CO insertion
An efficient method for the synthesis of amides via Pd-catalyzed oxidative carbonylation of C(sp3)-H bonds with CO and amines is described. The route efficiently provides substituted phenyl amides from alkanes.
Liu, Huizhen,Laurenczy, Gabor,Yan, Ning,Dyson, Paul J.
supporting information
p. 341 - 343
(2014/01/06)
Electronic properties of anticonvulsant amides. A C-13 nuclear magnetic resonance study of phenylacetanilides
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Yamagami,Takao,Takeuchi
p. 4172 - 4177
(2007/10/02)
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