52883-35-9Relevant articles and documents
4,5-Disubstituted-1,3-oxazolidin-2-imine derivatives: A new class of orally bioavailable nitric oxide synthase inhibitor
Ueda, Shigeo,Terauchi, Hideo,Yano, Akihiro,Ido, Motoharu,Matsumoto, Masashi,Kawasaki, Motoji
, p. 313 - 316 (2007/10/03)
In our search for a novel class of inducible nitric oxide synthase (iNOS) inhibitors, 1,3-oxazolidin-2-imine was found to weakly inhibit iNOS. Further modifications of this compound resulted in a remarkable increase in both the in vivo and in vitro inhibi
An efficient synthesis of a new series of acyclonucleosides starting from β-amino alcohols
Agami, Claude,Dechoux, Luc,Hamon, Louis,Melaimi, Mohand
, p. 6666 - 6669 (2007/10/03)
A series of new acyclonucleosides analogues 3 has been synthesized very efficiently in three steps starting from β-amino alcohols 1. The key step of this process is a nucleophilic substitution with various nucleophiles on 2,2'-anhydronucleosides 2. The chemo- and stereoselectivities of this reaction are discussed. AM1 calculations sustained the observed chemoselectivity.
One-pot conversion of alkenes into oxazolines and oxazolidin-2-ones promoted by diphenyl diselenide
Tiecco, Marcello,Testaferri, Lorenzo,Marini, Francesca,Temperini, Andrea,Bagnoli, Luana,Santi, Claudio
, p. 4131 - 4140 (2007/10/03)
Oxazolines or oxazolidin-Zones are produced from the reaction of diphenyl diselenide, ammonium persulfate and trifluoromethanesulfonic acid with alkenes in the presence of MeCN/H2O, NH2CN/H2O or NH2CO2Et.