528872-23-3

Basic information

• Product Name: benzoic acid, 4-bromo-2-nitro-, ethyl ester
• Synonyms: ethyl 4-bromo-2-nitrobenzoate;4-Bromo-2-nitro-benzoic acid ethyl ester
• CAS NO: 528872-23-3
• Molecular Formula: C₉H₈BrNO₄
• Molecular Weight: 274.07
• Mol File: 528872-23-3.mol

Chemical Properties

• Boiling Point: 340.1°C at 760 mmHg
• Flash Point: 159.5°C
• Density: 1.594g/cm³
• Vapor Pressure: 8.79E-05mmHg at 25°C
• Refractive Index: 1.576
• CAS DataBase Reference: benzoic acid, 4-bromo-2-nitro-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: benzoic acid, 4-bromo-2-nitro-, ethyl ester(528872-23-3)
• EPA Substance Registry System: benzoic acid, 4-bromo-2-nitro-, ethyl ester(528872-23-3)

Safety Data

• Hazardous Substances Data: 528872-23-3(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 99277-71-1 4-bromo-2-nitrobenzoic acid 

Downstream Products

• 117323-99-6 ethyl 2-amino-4-bromobenzoate 
• 1357149-96-2 ethyl 2-amino-4-(furan-2-yl)benzoate 

Relevant articles and documents

Efficient, Scalable Syntheses of Linker Molecules for Metal-Organic Frameworks

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The histamine H4 receptor is a G protein-coupled receptor that has attracted much interest for its role in inflammatory and immunomodulatory functions. In our search for new H4R ligands, a low affinity isoquinoline fragment was optimized to 7-(furan-2-yl)-4-(piperazin-1-yl) quinazolin-2-amine (VUF11489), as a new H4R antagonist. Analysis of its binding kinetics at the human H4R showed this compound to have a very different dissociative half-life in comparison with reference antagonist JNJ7777120.