99277-71-1

Basic information

• Product Name: 4-Bromo-2-nitrobenzoic acid
• Synonyms: 4-BROMO-2-NITROBENZOIC ACID;2-NITRO-4-BROMO BENZOIC ACID;4-Bromo-2-Nitrobenzoic Acid 2-Nitro-4-Bromobenzoic Acid;4-bromo-2-nitrobenzoic;Bromonitrobenzoicacid 42---;5-Bromo-2-carboxynitrobenzene;2-Bromo-2-nitrobenzoic acid
• CAS NO: 99277-71-1
• Molecular Formula: C₇H₄BrNO₄
• Molecular Weight: 246.01
• EINECS: 1312995-182-4
• Product Categories: blocks;Bromides;Carboxes;NitroCompounds;Multisubstituted Benzene;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;C7;Carbonyl Compounds;Carboxylic Acids;intermediate
• Mol File: 99277-71-1.mol
• Article Data: 16

Chemical Properties

• Melting Point: 165-169 °C
• Boiling Point: 368.6 °C at 760 mmHg
• Flash Point: 176.7 °C
• Appearance: /
• Density: 1.892 g/cm³
• Vapor Pressure: 4.38E-06mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: 1.97±0.25(Predicted)
• CAS DataBase Reference: 4-Bromo-2-nitrobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-2-nitrobenzoic acid(99277-71-1)
• EPA Substance Registry System: 4-Bromo-2-nitrobenzoic acid(99277-71-1)

Safety Data

• Hazard Codes: Xn,N,Xi
• Statements: 22-36/37/38-43-50
• Safety Statements: 26-36/37-61
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 2
• HazardClass: IRRITANT
• PackingGroup: III
• Hazardous Substances Data: 99277-71-1(Hazardous Substances Data)

Usage

Chemical Properties

Solid

Uses

Different sources of media describe the Uses of 99277-71-1 differently. You can refer to the following data:
1. 4-Bromo-2-nitrobenzoic acid is an intermediate in the synthesis of Lonafarnib (L469445), a potential anticancer agent.
2. Undergoes Negishi-type coupling with dimethylzinc in the presence of palladium-phosphine catalysis.

InChI:InChI=1/C7H4BrNO4/c8-4-1-2-5(7(10)11)6(3-4)9(12)13/h1-3H,(H,10,11)/p-1

Upstream product

• 610-36-6 4-amino-2-nitrobenzoic acid 
• 402948-06-5 3-(1H-benzoimidazol-2-yl)-4-hydroxy-1H-[1,7]naphthyridin-2-one 
• 5551-12-2 4-bromo-2-nitrobenzaldehyde 
• 106-38-7 para-bromotoluene 
• 88-72-2 1-methyl-2-nitrobenzene 
• 875-51-4 4-Bromo-2-nitroaniline 
• 60956-26-5 4-bromo-2-nitrotoluene 
• 79603-03-5 4-bromo-2-nitro-benzonitrile 

Downstream Products

• 20776-50-5 2-amino-4-bromobenzoic acid 
• 99847-13-9 3-nitrobiphenyl-4-carboxylic acid 
• 158580-57-5 methyl 4-bromo-2-nitrobenzoate 
• 929192-93-8 4-bromo-2-nitro-N-(3-pyrrolidin-1-ylpropyl)benzamide 
• 928839-70-7 4-bromo-N-(3-chlorophenyl)-2-nitrobenzamide 
• 1393456-12-6 C₁₅H₁₀BrNO₂S 
• 1413931-35-7 methyl 2-(8-bromo-3-(4-chlorophenyl)-5-oxo-2-thioxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-4(5H)-yl)-2-(4-chlorophenyl)acetate 
• 1413931-17-5 C₂₄H₁₇BrCl₂N₂O₄ 
• 1420990-58-4 C₂₁H₁₆F₂N₆O₂S 
• 1420990-50-6 3-benzyl-7-bromo-6-nitroquinazolin-4(3H)-one 
• 1420990-51-7 6-amino-3-benzyl-7-bromoquinazolin-4(3H)-one 
• 1420990-52-8 3-benzyl-7-bromo-6-[(4-chloro-5H-1,2,3-dithiazol-5-ylidene)amino]quinazolin-4(3H)-one 
• 194851-16-6 7-bromoquinazolin-4(3H)-one 
• 1429510-35-9 ethyl 5-(4-bromo-2-nitrophenyl)-1-[(S)-tetrahydrofuran-3-yl]-1H-pyrazole-4-carboxylate 

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