117323-99-6

Usage

InChI:InChI=1/C9H10BrNO2/c1-2-13-9(12)7-4-3-6(10)5-8(7)11/h3-5H,2,11H2,1H3

Upstream product

• 394-27-4 2-acetamido-4-fluorobenzoic acid 
• 101861-53-4 2-(methylcarbonylamino)-4-bromobenzoic acid 
• 64-17-5 ethanol 
• 20776-50-5 2-amino-4-bromobenzoic acid 
• 75-03-6 ethyl iodide 
• 99277-71-1 4-bromo-2-nitrobenzoic acid 
• 528872-23-3 ethyl 4-bromo-2-nitrobenzoate 
• 117324-10-4 2-acetylamino-4-iodobenzoic acid 

Downstream Products

• 20776-50-5 2-amino-4-bromobenzoic acid 
• 1357149-96-2 ethyl 2-amino-4-(furan-2-yl)benzoate 
• 1431937-02-8 C₂₀H₂₁N₃O₄S 
• 1431937-03-9 C₂₀H₁₉N₃O₄S 
• 1431936-93-4 C₁₂H₁₇NO₂ 
• 1431936-94-5 C₁₂H₁₅NO₂ 
• 1580483-77-7 C₁₇H₁₇NO₄S 
• 1580483-84-6 C₂₂H₁₆N₂O₄S 
• 1580483-78-8 C₂₄H₂₀N₂O₄S 
• 1580483-85-7 C₂₀H₁₇NO₄S 
• 1580483-79-9 C₂₂H₂₁NO₄S 
• 1580483-86-8 C₂₀H₁₇NO₄S 
• 1580483-80-2 C₂₂H₂₁NO₄S 
• 1580483-82-4 C₂₅H₂₁NO₄S 

Relevant academic research and scientific papers

Overcoming the Deallylation Problem: Palladium(II)-Catalyzed Chemo-, Regio-, and Stereoselective Allylic Oxidation of Aryl Allyl Ether, Amine, and Amino Acids

We report herein a Pd(II)/bis-sulfoxide-catalyzed intramolecular allylic C-H acetoxylation of aryl allyl ether, amine, and amino acids with the retention of a labile allyl moiety. Mechanistically, the reaction proceeds through a distinct double-bond isomerization from the allylic to the vinylic position followed by intramolecular carboxypalladation and the β-hydride elimination pathway. For the first time, C-H oxidation of N-allyl-protected amino acids to furnish five-membered heterocycles through 1,3-syn-addition is established with excellent diastereoselectivity.

PYRROL-1 -YL BENZOIC ACID DERIVATES USEFUL AS MYC INHIBITORS

The present invention provides compounds of Formula (I-A), (I-B), and (I-C), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting Myc (e.g., c-Myc) activity. The p

Ligand based design of novel histamine H4 receptor antagonists; Fragment optimization and analysis of binding kinetics

The histamine H4 receptor is a G protein-coupled receptor that has attracted much interest for its role in inflammatory and immunomodulatory functions. In our search for new H4R ligands, a low affinity isoquinoline fragment was optimized to 7-(furan-2-yl)-4-(piperazin-1-yl) quinazolin-2-amine (VUF11489), as a new H4R antagonist. Analysis of its binding kinetics at the human H4R showed this compound to have a very different dissociative half-life in comparison with reference antagonist JNJ7777120.

Quinazolin-4(3H)-one derivatives as anticoccidial agents

Variously substituted trans-3-[3-(3-hydroxypiperid-2-yl)-2-oxopropyl]quinazolin-4-(3H)-ones, a method of controlling or preventing coccidiosis in poultry therewith, intermediates therefor, and a process for the preparation of certain intermediates therefor.