530080-83-2

Basic information

• Product Name: 1-(4-Bromo-phenyl)-1,3-dihydro-imidazol-2-one
• Synonyms: 1-(4-Bromo-phenyl)-1,3-dihydro-imidazol-2-one
• CAS NO: 530080-83-2
• Molecular Formula: C₉H₇BrN₂O
• Molecular Weight: 237.97
• Mol File: 530080-83-2.mol

Chemical Properties

• Appearance: /
• Density: 1.637 g/cm³
• CAS DataBase Reference: 1-(4-Bromo-phenyl)-1,3-dihydro-imidazol-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Bromo-phenyl)-1,3-dihydro-imidazol-2-one(530080-83-2)
• EPA Substance Registry System: 1-(4-Bromo-phenyl)-1,3-dihydro-imidazol-2-one(530080-83-2)

Safety Data

• Hazardous Substances Data: 530080-83-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-(4-Bromo-phenyl)-1,3-dihydro-imidazol-2-one is used as a building block for the synthesis of bioactive compounds due to its unique chemical structure and properties. Its potential applications in the development of new drugs make it a valuable compound for pharmaceutical research and manufacturing.
Used in Chemical Synthesis:
1-(4-Bromo-phenyl)-1,3-dihydro-imidazol-2-one is used as a key intermediate in the synthesis of various chemical compounds, particularly those with pharmaceutical or biological activity. Its versatility in chemical reactions and compatibility with organic solvents facilitate its use in the creation of a wide range of products.
Used in Research and Development:
1-(4-Bromo-phenyl)-1,3-dihydro-imidazol-2-one serves as a subject of interest for researchers and manufacturers in the field of chemistry and pharmaceuticals. Its unique properties and potential applications make it a valuable compound for exploring new avenues in drug discovery and chemical innovation.

Upstream product

• 106-40-1 4-bromo-aniline 
• 2493-02-9 4-bromophenyl isocyanate 
• 22483-09-6 2,2-dimethoxyethylamine 

Downstream Products

• 1365802-98-7 1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3-dihydro-2H-imidazol-2-one 

Relevant articles and documents

CYCLIC UREAS AS INHIBITORS OF ROCK

The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.

DGAT1 INHIBITOR AND PREPARATION METHOD AND USE THEREOF

The present invention discloses a novel DGAT1 inhibitor, especially the compound of formula (I) or a pharmaceutically acceptable salt thereof, preparation and pharmaceutical composition thereof, as well as their uses in the preparation of a medicament for the prevention and treatment of Familial hyperchylomicronemia (FCS), obesity, hyperlipoproteinemia or hypertriglyceridemia.