54123-71-6

The invention discloses an iridium catalyst for catalyzing propargyl ester rearrangement to prepare substituted ketone compounds, and belongs to the field of chemical materials. The iridium catalyst TriaIrX2 (wherein X is Cl, Br or I) is synthesized from (2H-1, 2, 3-triazole-1-yl) acetic acid as a ligand and iridium, and the iridium catalyst has excellent catalytic activity on a rearrangement reaction of propargyl ester compounds under mild conditions, has more efficient catalytic performance compared with a traditional catalyst, can improve the stereoselectivity of the reaction, and can improve the synthesis yield of the unsaturated substituted ketone compound. In addition, the catalyst can also be used for a reaction of preparing substituted ketone compounds from benzyl alcohol compoundsand acetophenone compounds and a synthesis reaction of bisphenol F, and the application prospect of the catalyst is wide.

Under benzyl(chloro)bis triphenylphosphinepalladium(II) catalysis, α-oxygenated vinyltin compounds undergo clean cross coupling with acid chlorides to give α-oxygenated enones which are converted to unsymmetrical α-diketones, butadienyl ethers or substituted methyl vinyl ketones.