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Trimethyl(5-methyl-2-isopropylphenoxy)silane is an organosilicon compound with the chemical formula C13H22OSi. It is a colorless liquid at room temperature and is soluble in common organic solvents. Trimethyl(5-methyl-2-isopropylphenoxy)silane is characterized by a phenoxy group (C6H4O) with a 5-methyl and 2-isopropyl substitution pattern, which is connected to a trimethylsilyl group (Si(CH3)3). It is primarily used as a protecting group in organic synthesis, particularly for the protection of phenolic hydroxyl groups. The trimethylsilyl group can be easily introduced and removed under mild conditions, making it a valuable tool in the synthesis of complex organic molecules.

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  • 55012-80-1 Structure
  • Basic information

    1. Product Name: Trimethyl(5-methyl-2-isopropylphenoxy)silane
    2. Synonyms: Trimethyl(5-methyl-2-isopropylphenoxy)silane
    3. CAS NO:55012-80-1
    4. Molecular Formula: C13H22OSi
    5. Molecular Weight: 222.4
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 55012-80-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 255.2±19.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 0.894±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Trimethyl(5-methyl-2-isopropylphenoxy)silane(CAS DataBase Reference)
    10. NIST Chemistry Reference: Trimethyl(5-methyl-2-isopropylphenoxy)silane(55012-80-1)
    11. EPA Substance Registry System: Trimethyl(5-methyl-2-isopropylphenoxy)silane(55012-80-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 55012-80-1(Hazardous Substances Data)

55012-80-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 55012-80-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,5,0,1 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 55012-80:
(7*5)+(6*5)+(5*0)+(4*1)+(3*2)+(2*8)+(1*0)=91
91 % 10 = 1
So 55012-80-1 is a valid CAS Registry Number.

55012-80-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name trimethyl-(5-methyl-2-propan-2-ylphenoxy)silane

1.2 Other means of identification

Product number -
Other names Silane,trimethyl[5-methyl-2-(1-methylethyl)phenoxy]

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:55012-80-1 SDS

55012-80-1Downstream Products

55012-80-1Relevant articles and documents

Highly atom economical uncatalysed and I2-catalysed silylation of phenols, alcohols and carbohydrates, using HMDS under solvent-free reaction conditions (SFRC)

Jereb, Marjan

experimental part, p. 3861 - 3867 (2012/06/30)

An uncatalysed silylation of phenols, regardless on the aggregate state and nature of the substituents with 0.55 equiv of HMDS under solvent-free reaction conditions (SFRC) at room temperature is reported. Sterically hindered phenols, carbohydrates and most of the alcohols additionally required a catalytic amount (up to 2 mol %) of iodine. The reaction protocol is very simple; obtaining a pure product, particularly of uncatalysed reactions, was frequently a completely solvent-free process.

Synthesis, reactions, and spectral [NMR(1H, 13C, and 29Si), IR] studies of organosilicon aryloxides

Mishra,Singh

, p. 772 - 774 (2007/10/03)

Organosilicon aryloxides of the types MeaSi(OAr) and MeSi(OAr)3 (Ar = C6H4Bus-2; C6H3Me-2-Pri-5; C6H3Me-5-Pri-2) have been prepared, respectively, from reactions of appropriate phenols with Me3SiCl or MeSiCl3 in benzene using Et3N as a base. Reactions of Me3Si(OAr) with TiCl4 in 1:1 and 2:1 molar ratios in benzene afford derivatives TiCl3(OAr) and TiCl2(OAr)2, respectively. All these new derivatives have been characterized by elemental analyses, spectroscopic [IR, NMR (1H, 13C, and 29Si)] studies, as well as by molecular weight measurements.

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