55215-15-1

Basic information

• Product Name: 2-guanidinoethylphosphonic acid
• Synonyms: 2-guanidinoethylphosphonic acid
• CAS NO: 55215-15-1
• Molecular Formula: C3H10 N3 O3 P
• Molecular Weight: 167.1
• Mol File: 55215-15-1.mol

Chemical Properties

• Boiling Point: 462.9°C at 760 mmHg
• Flash Point: 233.8°C
• Appearance: /
• Density: 1.83g/cm³
• Vapor Pressure: 7.46E-10mmHg at 25°C
• Refractive Index: 1.634
• PKA: 2.09±0.10(Predicted)
• CAS DataBase Reference: 2-guanidinoethylphosphonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-guanidinoethylphosphonic acid(55215-15-1)
• EPA Substance Registry System: 2-guanidinoethylphosphonic acid(55215-15-1)

Safety Data

• Hazardous Substances Data: 55215-15-1(Hazardous Substances Data)

Usage

Uses

Used in Water Treatment Applications:
2-Guanidinoethylphosphonic acid serves as a chelating agent and corrosion inhibitor, playing a crucial role in managing metal ions and preventing scale formation in industrial water treatment processes.
Used in Bone Metabolism and Osteoporosis Prevention:
It has been studied for its potential impact on bone metabolism, with research indicating that it may contribute to the prevention of osteoporosis, thus offering a promising avenue for medical intervention in bone health.
Used in Antimicrobial Applications:
2-guanidinoethylphosphonic acid has demonstrated antibacterial and antiviral properties, suggesting its potential use in the development of treatments and preventative measures against infectious diseases.
Used in Flame Retardant Applications:
2-Guanidinoethylphosphonic acid has been investigated for its potential as a flame retardant in synthetic materials, which could enhance safety standards in various industries by reducing the risk of fire.
Used in Pharmaceutical Development:
Given its structural similarity to aminoethylphosphonic acid and its unique functional groups, 2-guanidinoethylphosphonic acid may also be explored for its potential in the development of new pharmaceuticals, particularly in areas where its specific chemical properties could offer therapeutic benefits.

InChI:InChI=1/C3H10N3O3P/c4-3(5)6-1-2-10(7,8)9/h1-2H2,(H4,4,5,6)(H2,7,8,9)

Upstream product

• 5324-30-1 diethyl 2-bromoethylphosphonate 
• 113-00-8 guanidine nitrate 
• 2041-14-7 (2-aminethyl)phosphonic acid 
• 53114-57-1 S-methylisothiourea hydrochloride 
• 16672-87-0 2-chloroethylphosphonic acid 

Relevant articles and documents

A new simple route to N-substituted 2-aminoethylphosphonic acids

2-Aminoethylphosphonic acid (AEPA) and its N-substituted compounds were prepared by one step reaction using 2-chloroethylphosphonic acid with ammonia and amines (H2NMe, HNMeMe, HNEtEt, H2NPr-n, H2NCH2ph,H2NCH2CH2NH2 and H2N(C=NH)NH2 in a dilute alkaline solution below 20 °C with simple work- up and easy purification. The reaction was accelerated by catalytic amount of potassium iodide. The yield for the reaction products were 35.6 to 48.6% for the KI absence and 78.2 to 88.0% for the KI presence.

ORGANOPHOSPHORUS COMPOUNDS AS POTENTIAL FUNGICIDES. PART II. AMINOALKANE-, GUANIDINOALKANE-, AND THIOUREIDOALKANE-PHOSPHONIC ACIDS: PREPARATION, SPECTROSCOPY, AND FUNGICIDAL ACTIVITY

A range of α-amino-, ω-amino-, α-guanidino-, and ω-guanidinoalkanephosphonic acids has been prepared for the purpose of studying their spectroscopic features and fungicidal activity.In addition, α-thioureido-octanephosphonic acid and thioureylene-1,1-bis(1-octanephosphonic acid) were isolated during the preparation of α-guanidino-octanephosphonic acid. 31P, 1H, and 13C nmr spectral data which were obtained for solutions of the amino- and guanidino-compounds in D2O or D2O/D2SO4, and for the thioureido compounds in DMSO-d6, are discussed together with previouslyreported data for the aminophosphonic types.FAB mass spectrometry generally gives strong pseudomolecular ions + for the zwitterionic amino- and guanidino-compounds with relatively simple fragmentations.Fungicidal activity of the α-aminophosphonic acids was found to be greater than for the ω-amino compounds, with maximum activity at a chain length of three carbon atoms when used as a seed dressing for the control of Drechslera spp.Moderately good activity was shown by the thioureido compounds against a number of fungal organisms in vitro but the guanidino-compounds exhibited low activity.Key words: Organophosphorus; fungicides; aminophosphonic acids; guanidinophosphonic acids; NMR spectroscopy; FAB mass spectroscopy.