562838-53-3

Basic information

• Product Name: 3-Benzhydryl-1-benzylpiperidin-4-one
• Synonyms: 3-Benzhydryl-1-benzylpiperidin-4-one
• CAS NO: 562838-53-3
• Molecular Formula: C₂₅H₂₅NO
• Molecular Weight: 355.4721
• Mol File: 562838-53-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Benzhydryl-1-benzylpiperidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Benzhydryl-1-benzylpiperidin-4-one(562838-53-3)
• EPA Substance Registry System: 3-Benzhydryl-1-benzylpiperidin-4-one(562838-53-3)

Safety Data

• Hazardous Substances Data: 562838-53-3(Hazardous Substances Data)

Upstream product

• 3612-20-2 1-phenylmethyl-4-piperidone 
• 776-74-9 Bromodiphenylmethane 
• 90-99-3 diphenylchloromethane 

Relevant articles and documents

RETRACTED ARTICLE: 3-Benzhydryl-4-piperidones as novel neurokinin-1 receptor antagonists and their efficient synthesis

A series of novel 3-benzhydryl-4-piperidone derivatives were identified as potent tachykinin neurokinin-1 (NK1) receptor antagonists. An efficient and versatile synthesis of this series was achieved with a coupling reaction of 1-benzylpiperidon

NITROGENOUS CYCLIC KETONE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE

A novel compound represented by the formula (I): wherein rings A and B each represents an optionally substituted aromatic ring, or rings A and B may be bonded to each other through linking between bonds or substituents thereof to form a ring; ring C represents a nitrogenous saturated heterocycle optionally having one or more substituents besides the oxo (provided that 2,3-dioxopyrrolidine ring is excluded); R1 represents hydrogen, an optionally substituted hydrocarbon group, or an optionally substituted heterocyclic group; and-------- indicates a single bond or a double bond. It has high antagonistic activity against a tachykinin receptor, especially an SP receptor.