56538-57-9

Basic information

• Product Name: 2-([(BENZYLOXY)CARBONYL]AMINO)-2-HYDROXYACETIC ACID
• Synonyms: Acetic acid, 2-hydroxy-2-[[(phenylmethoxy)carbonyl]amino]-;N-Carbobenzoxy-2-hydroxyglycine;ALPHA-HYDROXY-N-(BENZYLOXYCARBONYL) GLYCINE;2-([(BENZYLOXY)CARBONYL]AMINO)-2-HYDROXYACETIC ACID;CBZ-D,L-ALPHA-HYDROXYGLYCINE;N-CBZ-ALPHA-HYDROXYGLYCINE;[[(Benzyloxy)carbonyl]amino](hydroxy)acetic acid;2-Hydroxy-2-[[(phenylmethoxy)carbonyl]amino]acetic acid
• CAS NO: 56538-57-9
• Molecular Formula: C10H11NO5
• Molecular Weight: 225.2
• Product Categories: Thiazines ,Benzothiazoles,Thiazoles
• Mol File: 56538-57-9.mol

Chemical Properties

• Melting Point: 120-121℃
• Boiling Point: 470.3 °C at 760 mmHg
• Flash Point: 238.2 °C
• Appearance: /
• Density: 1.406
• Refractive Index: 1.582
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: 3.33±0.11(Predicted)
• CAS DataBase Reference: 2-([(BENZYLOXY)CARBONYL]AMINO)-2-HYDROXYACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-([(BENZYLOXY)CARBONYL]AMINO)-2-HYDROXYACETIC ACID(56538-57-9)
• EPA Substance Registry System: 2-([(BENZYLOXY)CARBONYL]AMINO)-2-HYDROXYACETIC ACID(56538-57-9)

Safety Data

• Hazardous Substances Data: 56538-57-9(Hazardous Substances Data)

Usage

Uses

Used in Organic Chemistry:
2-([(Benzyloxy)carbonyl]amino)-2-hydroxyacetic acid is used as a reagent for the protection of amine groups during peptide synthesis. The Boc protecting group allows for selective reactions to occur at the carboxyl group of the glycine residue, preventing unwanted side reactions at the amine group.
Used in Pharmaceutical Research:
2-([(Benzyloxy)carbonyl]amino)-2-hydroxyacetic acid is used as a building block in the synthesis of various pharmaceutical compounds. Its unique structure, including the Boc protecting group and hydroxyacetic acid moiety, enables the development of novel drug candidates with potential therapeutic applications.
Used in Chemical Reactions and Synthetic Processes:
2-([(Benzyloxy)carbonyl]amino)-2-hydroxyacetic acid is used as a versatile intermediate in various chemical reactions and synthetic processes. Its reactivity and functional groups allow for the formation of a wide range of compounds, making it a valuable tool in the field of organic synthesis.

InChI:InChI=1/C10H11NO5/c12-8(9(13)14)11-10(15)16-6-7-4-2-1-3-5-7/h1-5,8,12H,6H2,(H,11,15)(H,13,14)/t8-/m0/s1

Upstream product

• 621-84-1 O-benzyl carbamate 
• 6000-59-5 glyoxalic acid monohydrate 
• 298-12-4 Glyoxilic acid 
• 563-96-2 2,2-dihydroxyacetic acid 
• 3459-92-5 DBC 
• 501-53-1 benzyl chloroformate 
• 56-40-6 glycine 
• 4248-19-5 tert-butyl carbazate 
• 103711-22-4 α-(Isopropylthio)-Nα-(benzyloxycarbonyl)glycine 

Downstream Products

• 24469-05-4 D,L-homophenylalanine methyl ester 
• 58486-94-5 N-Benzyloxycarbonyl-β,β-diacetylalanin 
• 36747-66-7 D-α-benzyloxycarbonylamino-α-4-hydroxyphenylacetic acid 
• 42726-80-7 N-benzyloxycarbonyl-2-S-benzylthioglycine 
• 100945-15-1 N-(benzyloxycarbonyl)phosphonoglycine trimethyl ester 
• 127357-37-3 methyl 2-(benzyloxycarbonylamino)-2-methoxyacetate 
• 67809-41-0 N-Benzyloxycarbonyl-β,β-diacetylalaninmethylester 
• 83027-02-5 (Z)-2-Benzyloxycarbonylamino-3-phenyl-acrylic acid ethyl ester 
• 83026-99-7 2-Benzyloxycarbonylamino-2-diethyloxyphosphoryl-essigsaeure-ethylester 
• 80687-71-4 (E)-2-Benzyloxycarbonylamino-4-methyl-pent-2-enoic acid ethyl ester 
• 58486-95-6 N-Benzyloxycarbonyl-β-acetyl-β-benzoyl-alanin 
• 66381-07-5 Benzenesulfonyl-benzyloxycarbonylamino-acetic acid 
• 66381-10-0 ((benzyloxy)carbonyl)-C²-tosylglycine 

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