56825-91-3

Basic information

• Product Name: Phosphonic acid, (3-oxo-1,3-diphenylpropyl)-, dimethyl ester
• CAS NO: 56825-91-3
• Molecular Formula: C17H19O4P
• Molecular Weight: 318.309
• Mol File: 56825-91-3.mol

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, (3-oxo-1,3-diphenylpropyl)-, dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, (3-oxo-1,3-diphenylpropyl)-, dimethyl ester(56825-91-3)
• EPA Substance Registry System: Phosphonic acid, (3-oxo-1,3-diphenylpropyl)-, dimethyl ester(56825-91-3)

Safety Data

• Hazardous Substances Data: 56825-91-3(Hazardous Substances Data)

Upstream product

• 94-41-7 benzalacetophenone 
• 868-85-9 Dimethyl phosphite 
• 67-56-1 methanol 
• 121-45-9 phosphorous acid trimethyl ester 
• 614-47-1 1,3-diphenyl-propen-3-one 

Relevant articles and documents

PS-BEMP as a basic catalyst for the phospha-Michael addition to electron-poor alkenes

PS-BEMP was used as a heterogeneous catalyst for the phospha-Michael addition of phosphorus nucleophiles to a variety of electron-poor alkenes. The addition reactions were generally performed with equimolar amounts of reagents under solvent free conditions. The protocol proved to be very efficient for the addition to aromatic, non-aromatic and cyclic ketones, giving good yields (78-85%) in all cases. The protocol was also extended with good results to α,β-unsaturated esters and nitriles. This demonstrates that PS-BEMP is a good catalyst for the phospha-Michael addition to electron-poor alkenes.

Highly enantioselective 1,4- addition of diethyl phosphite to enones using a dinuclear Zn catalyst

An experiment was conducted to show highly enantioselectivities 1,4-addition of diethyl phosphite to enones through dinuclear zinc catalyst. The use of diethylzinc in combination with chiral ligands such as amino alcohols effectively led to chiral inducti

Selective Phosphorylation of Conjugated α-Enones at the Carbonyl Group, Catalyzed by Cyclohexylamine

Reaction of dialkyl phosphites with benzalacetophenone (chalcone) and benzalacetone in the presence of cyclohexylamine as a catalyst is a convenient preparative method for selective phosphorylation of conjugated α, β-unsaturated carbonyl compounds at the carbonyl group. The kinetics of cyclohexylamine-catalyzed addition of dialkyl phosphites to cis- and trans-chalcones is studied, and factors are revealed that influence the reactivity of addends in this reaction.

MECHANISM OF THE REACTION OF TRIALKYL PHOSPHITES WITH CHALCONES

According to our kinetic measurements the nucleophilic attack of trialkyl phosphite can occur both on the carbonyl carbon and on the C=C double bond of chalcone producing oxaphospholene ring.