578726-67-7

Basic information

• Product Name: 6-(DIETHYLAMINO)-3-PYRIDINYLALDEHYDE
• Synonyms: 6-(DIETHYLAMINO)-3-PYRIDINYLALDEHYDE;6-(Diethylamino)nicotinaldehyde
• CAS NO: 578726-67-7
• Molecular Formula: C10H14N2O
• Molecular Weight: 178.23
• Mol File: 578726-67-7.mol

Chemical Properties

• Boiling Point: 313.6 ºC at 760 mmHg
• Flash Point: 143.4 ºC
• Appearance: /
• Density: 1.078 g/cm³
• Vapor Pressure: 0.000492mmHg at 25°C
• Refractive Index: 1.575
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 5.39±0.10(Predicted)
• CAS DataBase Reference: 6-(DIETHYLAMINO)-3-PYRIDINYLALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(DIETHYLAMINO)-3-PYRIDINYLALDEHYDE(578726-67-7)
• EPA Substance Registry System: 6-(DIETHYLAMINO)-3-PYRIDINYLALDEHYDE(578726-67-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 578726-67-7(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
6-(DIETHYLAMINO)-3-PYRIDINYLALDEHYDE is utilized as a key intermediate in organic synthesis, serving as a building block for the creation of a wide range of chemical compounds. Its structural features make it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 6-(DIETHYLAMINO)-3-PYRIDINYLALDEHYDE is used as a precursor in the development of various drugs. Its unique chemical properties allow it to be incorporated into medicinal compounds, potentially enhancing their therapeutic effects.
Used in Agrochemicals:
6-(DIETHYLAMINO)-3-PYRIDINYLALDEHYDE also finds application in the agrochemical sector, where it is employed in the synthesis of pesticides and other agricultural chemicals. Its role in these products contributes to their effectiveness in protecting crops and enhancing agricultural yields.
Used in Fluorescent Dyes:
6-(DIETHYLAMINO)-3-PYRIDINYLALDEHYDE is used in the preparation of fluorescent dyes, capitalizing on its ability to emit light upon exposure to certain wavelengths. This property makes it suitable for applications that require visual distinction or detection at the molecular level.
Used as a Fluorescence Reagent in Analytical Chemistry:
6-(DIETHYLAMINO)-3-PYRIDINYLALDEHYDE functions as a fluorescence reagent in analytical chemistry, where its fluorescent properties are harnessed for the detection and quantification of various substances. This application is particularly useful in research and quality control processes.
Used in Antimicrobial Applications:
6-(DIETHYLAMINO)-3-PYRIDINYLALDEHYDE has been studied for its antimicrobial properties, indicating its potential use in combating microbial infections. Its ability to inhibit the growth of certain microorganisms positions it as a candidate for further development in the field of antimicrobial agents.
Used in Antitumor Research:
6-(DIETHYLAMINO)-3-PYRIDINYLALDEHYDE has also demonstrated antitumor properties, making it a subject of interest in cancer research. Its potential to affect tumor growth and progression is currently under investigation, with the aim of developing new therapeutic strategies for cancer treatment.

InChI:InChI=1/C10H14N2O/c1-3-12(4-2)10-6-5-9(8-13)7-11-10/h5-8H,3-4H2,1-2H3

Upstream product

• 109-89-7 diethylamine 
• 149806-06-4 6-bromonicotinaldehyde 
• 774239-06-4 6-fluoro-N-methoxy-N-methylpyridine-3-carboxamide 
• 403-45-2 6-fluoronicotinic acid 

Relevant articles and documents

Fluorescent compound having affinity with Abeta oligomer, and preparation method and application thereof

The invention discloses a fluorescent compound having affinity with an Abeta oligomer, and discloses a preparation method and application of the fluorescent compound. The maximum excitation spectrum value and the fluorescence emission spectrum value of th

5-(1 H-BENZO[D]IMIDAZO-2-YL)-PYRIDIN-2-AMINE AND 5-(3H-IMIDAZO[4,5-B]PYRIDIN-6-YL)-PYRIDIN-2-AMINE DERIVATIVES AS C-MYC AND P300/CBP HISTONE ACETYLTRANSFERASE INHIBITORS FOR TREATING CANCER

The invention is directed to substituted 5-(1H-benzo[d]imidazo-2-yl)- pyridin-2-amine and 5-(3H-imidazo[4,5-b]pyridin-6-yl)-pyridin-2-amine derivatives. Specifically, the invention is directed to compounds according to Formula (lb) wherein R', R2', R3', R4', Rs', R6', R7', and X1' are as defined herein; or a salt thereof including a pharmaceutically acceptable salt thereof. The compounds of the invention decrease MYC protein (c-MYC) in cells and/or inhibit p300/CBP histone acetyltransferase and can be useful in the treatment of cardiac hypertrophy, diabetes, obesity and nonalcoholic fatty liver disease, HIV, polycystic kidney disease, inflammatory diseases, ankylosing spondylitis, psoriasis, psoriatic arthritis, rheumatoid arthritis, Crohn's disease, multiple sclerosis, cancer and pre-cancerous syndromes, and diseases associated with dysregulation of Myc or inhibition of p300/CBP histone acetyltransferase. Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention still further discloses methods of reducing MYC protein (c-MYC) in cells and inhibiting p300/CBP histone acetyltransferase activity, and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.

ANTIBACTERIAL COMPOUNDS AND USES THEREOF

The present invention relates to compounds of formula (I) including any stereochemically isomeric form thereof, or pharmaceutically acceptable salts thereof, for the treatment of tuberculosis.