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592552-25-5

Urea, N-[2-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethoxy]phenyl]-N'-[(3R)-1-[( 6-fluoro-2-naphthalenyl)methyl]-3-pyrrolidinyl]- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • Urea, N-[2-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethoxy]phenyl]-N'-[(3R)-1-[( 6-fluoro-2-naphthalenyl)methyl]-3-pyrrolidinyl]-

    Cas No: 592552-25-5

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  • Urea, N-[2-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethoxy]phenyl]-N'-[(3R)-1-[( 6-fluoro-2-naphthalenyl)methyl]-3-pyrrolidinyl]-

    Cas No: 592552-25-5

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  • 592552-25-5 Structure

  • Basic information

    1. Product Name: Urea, N-[2-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethoxy]phenyl]-N'-[(3R)-1-[( 6-fluoro-2-naphthalenyl)methyl]-3-pyrrolidinyl]-
    2. Synonyms:
    3. CAS NO:592552-25-5
    4. Molecular Formula: C30H40FN3O3Si
    5. Molecular Weight: 537.75
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 592552-25-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Urea, N-[2-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethoxy]phenyl]-N'-[(3R)-1-[( 6-fluoro-2-naphthalenyl)methyl]-3-pyrrolidinyl]-(CAS DataBase Reference)
    10. NIST Chemistry Reference: Urea, N-[2-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethoxy]phenyl]-N'-[(3R)-1-[( 6-fluoro-2-naphthalenyl)methyl]-3-pyrrolidinyl]-(592552-25-5)
    11. EPA Substance Registry System: Urea, N-[2-[2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]ethoxy]phenyl]-N'-[(3R)-1-[( 6-fluoro-2-naphthalenyl)methyl]-3-pyrrolidinyl]-(592552-25-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 592552-25-5(Hazardous Substances Data)

592552-25-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 592552-25-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,9,2,5,5 and 2 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 592552-25:
(8*5)+(7*9)+(6*2)+(5*5)+(4*5)+(3*2)+(2*2)+(1*5)=175
175 % 10 = 5
So 592552-25-5 is a valid CAS Registry Number.

592552-25-5Downstream Products

592552-25-5Relevant articles and documents

Pyrrolidinyl phenylurea derivatives as novel CCR3 antagonists

Nitta, Aiko,Iura, Yosuke,Inoue, Hideki,Imaoka, Takayuki,Takahashi, Toshiya,Sato, Ippei,Morihira, Koichiro,Kubota, Hirokazu,Morokata, Tatsuaki,Takeuchi, Makoto,Ohta, Mitsuaki,Tsukamoto, Shin-Ichi

, p. 6876 - 6881,6 (2020/09/02)

Optimization starting with our lead compound 1 (IC50 = 4.9 nM) led to the identification of pyrrolidinyl phenylurea derivatives. Further modification toward improvement of the bioavailability provided (R)-1-(1-((6-fluoronaphthalen-2-yl)methyl)pyrrolidin-3-yl)-3-(2-(2- hydroxyethoxy)phenyl)urea 32 (IC50 = 1.7 nM), a potent and orally active CCR3 antagonist.

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