16365-25-6

Basic information

• Product Name: 2-(2-NITROPHENOXY)ETHANOL
• Synonyms: 2-NITROPHENOXY ETHANOL;2-(2-NITROPHENOXY)ETHANOL;AKOS B030716
• CAS NO: 16365-25-6
• Molecular Formula: C₈H₉NO₄
• Molecular Weight: 183.16
• Mol File: 16365-25-6.mol
• Article Data: 17

Chemical Properties

• Melting Point: 35-36 °C
• Boiling Point: 180-182 °C(Press: 4 Torr)
• Appearance: /
• Density: 1.314±0.06 g/cm3(Predicted)
• PKA: 14.10±0.10(Predicted)
• CAS DataBase Reference: 2-(2-NITROPHENOXY)ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-NITROPHENOXY)ETHANOL(16365-25-6)
• EPA Substance Registry System: 2-(2-NITROPHENOXY)ETHANOL(16365-25-6)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 16365-25-6(Hazardous Substances Data)

Usage

Functional Groups

Nitro group, phenoxy group

Molecular Structure

An ethanol chain with a nitro group and a phenoxy group attached to a central carbon atom

Usage

Starting material in the synthesis of pharmaceuticals and agrochemicals, solvent in chemical reactions

Toxicity

Toxic if ingested, inhaled, or absorbed through the skin

Safety Precautions

Handle with care and wear protective equipment such as gloves and a respirator.

Upstream product

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Downstream Products

• 16365-35-8 o-Nitro-phenyl-β-n-pentyloxy-methoxy-ethylether 
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• 16365-34-7 o-Nitro-phenyl-β-isopentyloxy-methoxyethylether 
• 16364-87-7 β-Cyan-β'-o-nitro-phenoxy-diethylether 
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• 16365-33-6 o-Nitro-phenyl-β-n-butyloxy-methoxy-ethylether 
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Relevant articles and documents

Chemoselective hydrosilylation of carboxylic acids using a phosphine-free ruthenium complex and phenylsilane

A highly chemoselective hydrosilylation of carboxylic acids was achieved using a bench-stable, phosphine-free Ru-complex tethered with hemi-labile thiophene ligands as the catalyst, employing phenylsilane as the reducing agent. The methodology was further elaborated towards the one-pot synthesis of indole and benzoxazine via tandem reduction/cyclization of acid and nitro group.

METHODS FOR PREPARING FUEL ADDITIVES

A method is provided for preparing a fuel additive having the formula: ( l ) The method comprises carrying out the following reactions: (i) addition of an alkylating agent b to starting material a: (a) to form an intermediate c; and (ii) ring closing intermediate c to form fuel additive e.

Toward the Rational Design of Galactosylated Glycoclusters That Target Pseudomonas aeruginosa Lectin A (LecA): Influence of Linker Arms That Lead to Low-Nanomolar Multivalent Ligands

Anti-infectious strategies against pathogen infections can be achieved through antiadhesive strategies by using multivalent ligands of bacterial virulence factors. LecA and LecB are lectins of Pseudomonas aeruginosa implicated in biofilm formation. A series of 27 LecA-targeting glycoclusters have been synthesized. Nine aromatic galactose aglycons were investigated with three different linker arms that connect the central mannopyranoside core. A low-nanomolar (Kd=19 nm, microarray) ligand with a tyrosine-based linker arm could be identified in a structure–activity relationship study. Molecular modeling of the glycoclusters bound to the lectin tetramer was also used to rationalize the binding properties observed.