NOVEL INDOLE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
The present invention provides a novel indole derivative compound, an isomer thereof, a pharmaceutically acceptable salt thereof, or a hydrate or solvate thereof. The compound according to the present invention can selectively inhibit histone deacetylase (HDAC), and thus can be used to effectively treat a disease associated with histone deacetylase (HDAC) activity.
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Paragraph 1018-1020
(2015/07/16)
A general method for C3 reductive alkylation of indoles
General indole C3 reductive alkylation conditions have been developed. The scope of this reaction includes C2 unsubstituted indoles, aryl and alkyl aldehydes, as well as N-H and N-alkyl indole substrates.
Mahadevan, Anu,Sard, Howard,Gonzalez, Mario,McKew, John C.
p. 4589 - 4591
(2007/10/03)
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