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CHROMAN-3-YLAMINE, a nitrogen-containing compound with a chroman core structure and an amine functional group, is a chemical compound belonging to the chroman family. With the chemical formula C10H11NO, it is recognized for its potential applications in medicinal chemistry and drug discovery. CHROMAN-3-YLAMINE can act as a building block for synthesizing various biologically active molecules and has been studied for its pharmacological activities, such as anti-inflammatory and antitumor properties. It is a versatile chemical with promising prospects for pharmaceutical research and development.

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  • 60575-19-1 Structure
  • Basic information

    1. Product Name: CHROMAN-3-YLAMINE
    2. Synonyms: 3,4-dihydro-3-amino-2H-1-benzopyran;CHROMAN-3-YLAMINE;CHROMAN-3-AMINE;3,4-dihydro-2H-chroMen-3-aMine;3,4-Dihydro-2H-1-benzopyran-3-amine;3-Aminochroman;2H-1-BENZOPYRAN-3-AMINE,3,4-DIHYDRO-
    3. CAS NO:60575-19-1
    4. Molecular Formula: C9H11NO
    5. Molecular Weight: 149.19
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 60575-19-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 256.8 °C at 760 mmHg
    3. Flash Point: 117.9 °C
    4. Appearance: /
    5. Density: 1.106 g/cm3
    6. Vapor Pressure: 0.0151mmHg at 25°C
    7. Refractive Index: 1.559
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: CHROMAN-3-YLAMINE(CAS DataBase Reference)
    11. NIST Chemistry Reference: CHROMAN-3-YLAMINE(60575-19-1)
    12. EPA Substance Registry System: CHROMAN-3-YLAMINE(60575-19-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 60575-19-1(Hazardous Substances Data)

60575-19-1 Usage

Uses

Used in Pharmaceutical Research and Development:
CHROMAN-3-YLAMINE is used as a building block for the synthesis of biologically active molecules due to its versatile chemical structure and potential to contribute to the development of new drugs.
Used in Medicinal Chemistry:
CHROMAN-3-YLAMINE is utilized as a key component in the design and synthesis of pharmaceutical compounds, particularly those with anti-inflammatory and antitumor properties, owing to its pharmacological activity.
Used in Drug Discovery:
As a compound with demonstrated potential in medicinal chemistry, CHROMAN-3-YLAMINE is used in drug discovery processes to identify and develop new therapeutic agents with improved efficacy and safety profiles.

Check Digit Verification of cas no

The CAS Registry Mumber 60575-19-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,0,5,7 and 5 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 60575-19:
(7*6)+(6*0)+(5*5)+(4*7)+(3*5)+(2*1)+(1*9)=121
121 % 10 = 1
So 60575-19-1 is a valid CAS Registry Number.
InChI:InChI=1/C9H11NO/c10-8-5-7-3-1-2-4-9(7)11-6-8/h1-4,8H,5-6,10H2

60575-19-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,4-dihydro-2H-chromen-3-amine

1.2 Other means of identification

Product number -
Other names 3,4-dihydro-2H-1-benzopyran-3-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:60575-19-1 SDS

60575-19-1Downstream Products

60575-19-1Relevant articles and documents

POTENT SMALL MOLECULE INHIBITORS OF AUTOPHAGY, AND METHODS OF USE THEREOF

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Page/Page column 116; 117, (2014/09/29)

Certain aspects of the invention relate to small molecule autophagy inhibitors, and their use for treatment and prevention of cancers and acute pancreatitis. Medicinal chemistry studies led to small molecular autophagy inhibitors with improved potency and selectivity.

ANTAGONISTS OF THE TRPV1 RECEPTOR AND USES THEREOF

-

Page/Page column 13, (2008/12/06)

The present application is directed to compounds that are TRPV1 antagonists and have formula (I) wherein variables Ar1, L1, R1, R2, R3, R4, R5, Y1, Y2, and Y3, are as defined in the description, which are useful for treating disorders caused by or exacerbated by vanilloid receptor activity.

Chromanylurea compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor and uses thereof

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Page/Page column 23, (2008/06/13)

Compounds that are antagonists of the VR1 receptor, having formula (I) [image] or a pharmaceutically acceptable salt, prodrug, or salt of a prodrug thereof, wherein A1, A2, A3, A4, R7, R8, R9, X, Y, Z, L, n, and m, are as defined herein, and are useful in disorders prevented or ameliorated by inhibiting the VR1 receptor.

Centrally acting 6,7,8,9-tetrahydro-3H-benz(E)indole heterocyclics

-

, (2008/06/13)

A compound of Formula I STR1 or pharmaceutically acceptable salts of Formula I, where R1 is H, C1 -C3 alkyl, --(CH2)n CONH2 where n is 2 to 6, (CH2)n -1-(4,4-dimethylpiperidine-2

3,4-Dihydro-3-amino-2H-1-benzopyran Derivatives as 5-HT1A Receptor Ligands and Potential Anxiolytic Agents. 1. Synthesis and Structure-Activity Relationship Studies

Podona, Tchao,Guardiola-Lemaitre, Beatrice,Caignard, Daniel-Henri,Adam, Gerard,Pfeiffer, Bruno,et al.

, p. 1779 - 1793 (2007/10/02)

A series of 3,4-dihydro-3-amino-2H-1-benzopyran derivatives were prepared in order to determine the necessary structural requirements for good affinity for 5-HT1A receptors and high selectivity versus other receptors.Modifications of the extrac

Centrally acting 6,7,8,9-tetrahydro-3H-benz(e)indole heterocyclics

-

, (2008/06/13)

A compound of Formula I STR1 or pharmaceutically acceptable salts of Formula I, where R 1 is H, C 1 -C 3 alkyl, --(CH 2) n CONH 2 where n is 2 to 6, (CH2) n -1-(4,4-dimethylpiperidine-2,6-dione-yl), or cyclopropylmethyl;R 2 is hydrogen, C 1 -C 8 alkyl, C

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