cas 61727-33-1, 5-Chloro-2-(methylthio)pyrimidine-4-carboxylic acid | Articles data ｜lookchem

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61727-33-1

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General and facial synthesis of 2-amino-5-halogenpyrimidine-4-carboxylic acids and their derivatives
A facile synthetic approach to 2-amino-5-halogen-pyrimidine-4-carboxylic acids from 5-halogen-2-methylsulfonylpyrimidine-4-carboxylic acid by nucleophilic displacement of the methylsulfonyl group with primary and secondary aliphatic amines has been develo
Blyumin, Evgeniy V.,Neunhoeffer, Hans,Volovenko, Yulian V.
p. 2231 - 2241
(2008/02/07)

Efficient synthesis of a new pyrimidine derivative
A ready preparation for a new pyrimidine derivative, 2-aminomethyl-5-chloropyrimidine, from s-methylthiouronium sulphate and mucochloric acid is reported.
Liang, Yong-Min,Luo, Sheng-Jun,Zhang, Zhao-Xin,Ma, Yong-Xiang
p. 153 - 157
(2007/10/03)

On the synthesis of 4- and 5-pyrimidinyl-diphenyl-(1-imidazolyl)methanes and their antifungal activity
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Budesinsky,Vavrina,Langsadl,Holubek
p. 539 - 547
(2007/10/02)

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Chemical Properties

Melting Point: 204-205 ºC
Boiling Point: 396.4°C at 760 mmHg
Flash Point:193.5°C
Density: 1.59g/cm³
Solubility:soluble in Methanol
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Vapor Pressure: 5.4E-07mmHg at 25°C
PKA: 1.20±0.25(Predicted)
PSA: 88.38000
LogP: 1.55010

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