62432-97-7

Basic information

• Product Name: 6,6-dimethyl-4-morpholin-4-yl-5,6-dihydropyridine-2(1H)-thione
• CAS NO: 62432-97-7
• Molecular Formula: C₁₁H₁₈N₂OS
• Molecular Weight: 226.3384
• Mol File: 62432-97-7.mol

Chemical Properties

• Boiling Point: 323.2°C at 760 mmHg
• Flash Point: 149.3°C
• Density: 1.17g/cm³
• Vapor Pressure: 0.000265mmHg at 25°C
• Refractive Index: 1.59
• CAS DataBase Reference: 6,6-dimethyl-4-morpholin-4-yl-5,6-dihydropyridine-2(1H)-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 6,6-dimethyl-4-morpholin-4-yl-5,6-dihydropyridine-2(1H)-thione(62432-97-7)
• EPA Substance Registry System: 6,6-dimethyl-4-morpholin-4-yl-5,6-dihydropyridine-2(1H)-thione(62432-97-7)

Safety Data

• Hazardous Substances Data: 62432-97-7(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 59743-23-6 4-(dimethylamino)-5,6-dihydro-6,6-dimethyl-2(1H)-pyridinthione 
• 77747-72-9 5,6-Dihydro-4-hydroxy-6,6-dimethyl-2(1H)-pyridinthion 
• 55113-93-4 morpholine-4-carbothioic acid 1,1-dimethyl-3-oxo-butylamide 
• 141-79-7 4-methyl-pent-3-en-2-one 
• 22390-67-6 morpholinium thiocyanate 

Downstream Products

• 77747-74-1 4-Aminodihydro-2(1H)-pyridinthion 
• 77747-72-9 5,6-Dihydro-4-hydroxy-6,6-dimethyl-2(1H)-pyridinthion 
• 58913-37-4 4-methylamino-6,6-dimethyl-5,6-dihydropyridine-2(1H)-thione 
• 58913-46-5 6,6-dimethyl-4-(phenylamino)-5,6-dihydropyridine-2(1H)-thione 
• 77747-76-3 4-Hydroxy-6,6-dimethyl-5,6-dihydro-2(1H)-pyridon 

Relevant articles and documents

Synthesis of new tetrahydropyridinylidene ammonium salts and their antiprotozoal potency

Several new tetrahydropyridinylidene ammonium salts were prepared by selective reduction. They were characterized using UV-Vis spectroscopy, FT-IR spectroscopy, and HRMS. Their structure was established by NMR spectroscopy and a single X-ray structure ana

4-Hydroxy-6,6-dimethyl-5,6-dihydro-2(1H)-pyridinethione and -one and the Corresponding Tautomers

The tautomers, 4-hydroxy-5,6-dihydro-6,6-dimethyl-2(1H)-pyridinethione (1) and 6,6-dimethyl-2-thioxo-4-piperidone (2) resp., and 4-hydroxy-5,6-dihydro-6,6-dimethyl-2(1H)-pyridone (9) and 6,6-dimethyl-2,4-piperidinedione (10) resp. were synthesized by hydrolysis of 4-amino-5,6-dihydro-6,6-dimethyl-2(1H)-pyridinethiones (4,5) and -ones (11,12). 1,2 and 9,10 undergo an aminolysis in amines to the corresponding 4-aminodihydro-2(1H)-pyridinethiones 4,5 and -ones 11, 12 resp. - Keywords: 6,6-Dimethyl-2,4-piperidindione; 6,6-Dimethyl-2-thioxo-4-piperidone; 4-Hydroxy-6,6-dimethyl-5,6-dihydro-2(1H)-pyridone, and -pyridinethione; Keto-enol-tautomeris m

2,4-Diaminodihydropyridines (Heterocyclic Compounds, 67. Comm.)

Aminolysis of 4-alkylamino- and 4-dialkylamino-2-methylthiodihydropyridines (*Hl) 1, 2 resp. under various reaction-condition leads to assymmetrically or symmetrically substituted 2,4-bisalkylamino- or 2,4-bisdialkylamino- and 2-alkylamino-4-dialkylamino- or 2-dialkylamino-4-alkylaminodihydropyridines 3, 4, 5, 6 resp.On treatment with alkali only the aminogroup in pos.4 of the pyridines 3, 4, 5, 6 is hydrolyzed and 4-hydroxy-2-aminopyridines 9 are formed.Different substituted 2,4-diaminodihydropyridines 3, 4, 5, 6 can also be synthesized by reaction of 4-hydroxy-2-aminopyridines (*HCl) 9 with amines.Also the aminolysis of 4-alkylamino- and 4-dialkylaminodihydropyridinthiones 7, 8 resp. is described. - Keywords: 2-Alkylamino-4-dialkylamino-5,6-dihydropyridines, synthesis; Alkyl- and arylaminopyridine derivatives, reaction with prim. and sec. amines; Aminolysis of alkyl-, and arylaminopyridine derivatives; 2,4-Bisalkylamino-5,6-dihydropyridines, synthesis; 2,4-Bisdialkylamino-5,6-dihydropyridines, synthesis; 2-Dialkylamino-4-alkylamino-5,6-pyridines, synthesis.

Synthesis of Heterocyclic Compounds via Enamines. Part 8. Acid-catalysed Transformations in 4,4,6-Trimethyl-1,4-Dihydropyrimidine-2(3H)-thione Derivatives and Related Compounds

1-Substituted 4,4,6-trimethyl-1,4-dihydropyrimidine-2(3H)-thiones (2) on heating in 11M-HCl at 100-110 deg C are converted into the corresponding 2-substituted-amino-4,6,6-trimethyl-6H-1,3-thiazines (4) and/or thioureas.But at 95-100 deg C, Dimroth rearrangement products, e.g. the corresponding 2-substituted-amino-4,4,6-trimethyl-4H-1,3-thiazenes (3) are formed.