Welcome to LookChem.com Sign In|Join Free

CAS

  • or
4H-PYRAN-4-ONE, 3-FLUOROTETRAHYDROis a heterocyclic chemical compound belonging to the pyranone family, distinguished by the presence of a fluorine atom and a tetrahydro group. 4H-PYRAN-4-ONE, 3-FLUOROTETRAHYDROis known for its unique properties, such as increased stability and altered reactivity due to the fluorine atom, making it valuable in organic synthesis and medicinal chemistry. Its potential pharmacological properties, including effects on the central nervous system and as an anti-inflammatory agent, further broaden its applications in the chemical and pharmaceutical industries.

624734-19-6

Post Buying Request

624734-19-6 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

624734-19-6 Usage

Uses

Used in Organic Synthesis:
4H-PYRAN-4-ONE, 3-FLUOROTETRAHYDROis used as a key intermediate in organic synthesis for the development of various chemical compounds. Its unique structure and properties facilitate specific chemical reactions, contributing to the synthesis of complex organic molecules.
Used in Medicinal Chemistry:
In the pharmaceutical industry, 4H-PYRAN-4-ONE, 3-FLUOROTETRAHYDROis utilized as a building block for the design and synthesis of new pharmaceutical agents. Its potential pharmacological properties make it a promising candidate for the development of drugs targeting the central nervous system and as anti-inflammatory agents.
Used in Chemical Reactions:
4H-PYRAN-4-ONE, 3-FLUOROTETRAHYDROis employed as a reactant in various chemical reactions due to its unique reactivity imparted by the fluorine atom. This allows for the formation of new compounds with specific properties, useful in different chemical applications.
Used in Drug Development:
4H-PYRAN-4-ONE, 3-FLUOROTETRAHYDROis used as a potential active pharmaceutical ingredient in drug development. Its pharmacological properties are being studied for the treatment of various conditions, particularly those related to the central nervous system and inflammation.

Check Digit Verification of cas no

The CAS Registry Mumber 624734-19-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,2,4,7,3 and 4 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 624734-19:
(8*6)+(7*2)+(6*4)+(5*7)+(4*3)+(3*4)+(2*1)+(1*9)=156
156 % 10 = 6
So 624734-19-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H7FO2/c6-4-3-8-2-1-5(4)7/h4H,1-3H2

624734-19-6 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Aldrich

  • (SYX00096)  3-Fluorodihydro-2H-pyran-4(3H)-one  AldrichCPR

  • 624734-19-6

  • SYX00096-1G

  • 7,411.95CNY

  • Detail

624734-19-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Fluorodihydro-2H-pyran-4(3H)-one

1.2 Other means of identification

Product number -
Other names 3-fluorooxan-4-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:624734-19-6 SDS

624734-19-6Relevant articles and documents

SUBSTITUTED AMINOPURINE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

-

, (2016/05/02)

Provided herein are Aminopurine Compounds having the following structures: wherein R1, R2, and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound, and methods for treating or preventing a cancer, for example, melanoma.

GEMINALLY SUBSTITUTED CYANOETHYLPYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS

-

Page/Page column 86; 87, (2014/10/03)

The instant invention provides compounds of Formula (I) which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

SERINE/THREONINE KINASE INHIBITORS

-

Paragraph 0245-0246, (2014/03/25)

Compounds having the formula I wherein R2, X and Z as defined herein are inhibitors of ERK kinase. Also disclosed are compositions and methods for treating hyperproliferative disorders.

CHEMOKING RECEPTOR ANTAGONISTS

-

, (2013/03/26)

Disclosed herein are chemokine receptor antagonists of formula (I) wherein G1, X1, X2, and X3 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.

QUINAZOLINE COMPOUNDS AS SERINE/THREONINE KINASE INHIBITORS

-

Paragraph 00220, (2013/03/26)

Compounds having the formula (I) wherein R1, R2, R3 and Ar as defined herein are inhibitors of ERK kinase. Also disclosed are compositions and methods for treating hyperproliferative disorders.

SERINE/THREONINE KINASE INHIBITORS

-

Paragraph 00254, (2013/09/12)

Compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof are provided, which are useful for the treatment of hyperproliferative, pain and inflammatory diseases. Methods of using compounds of Formula I or a stereoisomer, tautomer, prodrug or pharmaceutically acceptable salt thereof, for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions are disclosed.

Enantioselective organocatalytic α-fluorination of cyclic ketones

Kwiatkowski, Piotr,Beeson, Teresa D.,Conrad, Jay C.,MacMillan, David W. C.

supporting information; body text, p. 1738 - 1741 (2011/04/17)

The first highly enantioselective α-fluorination of ketones using organocatalysis has been accomplished. The long-standing problem of enantioselective ketone α-fluorination via enamine activation has been overcome via high-throughput evaluation of a new library of amine catalysts. The optimal system, a primary amine functionalized Cinchona alkaloid, allows the direct and asymmetric α-fluorination of a variety of carbo- and heterocyclic substrates. Furthermore, this protocol also provides diastereo-, regio-, and chemoselective catalyst control in fluorinations involving complex carbonyl systems.

NOVEL CCR2 RECEPTOR ANTAGONISTS, METHOD FOR PRODUCING THE SAME, AND USE THEREOF AS MEDICAMENTS

-

Page/Page column 94, (2011/12/02)

The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) of formula (I) wherein HET is a group selected from among formulas (IIa) (IIb) (IIc) (IId) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD and pain diseases.

NEW CCR2 RECEPTOR ANTAGONISTS, METHOD FOR PRODUCING THE SAME, AND USE THEREOF AS MEDICAMENTS

-

Page/Page column 75-76, (2011/12/02)

The present invention relates to novel antagonists for CCR2 (CC chemokine receptor 2) and their use for providing medicaments for treating conditions and diseases, especially pulmonary diseases like asthma and COPD and pain diseases

Design, synthesis, and structure-activity relationship of novel CCR2 antagonists

Kothandaraman, Shankaran,Donnely, Karla L.,Butora, Gabor,Jiao, Richard,Pasternak, Alexander,Morriello, Gregori J.,Goble, Stephen D.,Zhou, Changyou,Mills, Sander G.,MacCoss, Malcolm,Vicario, Pasquale P.,Ayala, Julia M.,DeMartino, Julie A.,Struthers, Mary,Cascieri, Margaret A.,Yang, Lihu

scheme or table, p. 1830 - 1834 (2009/11/30)

A series of novel 1-aminocyclopentyl-3-carboxyamides incorporating substituted tetrahydropyran moieties have been synthesized and subsequently evaluated for their antagonistic activity against the human CCR2 receptor. Among them analog 59 was found to posses potent antagonistic activity.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 624734-19-6