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But-2-yne-1,4-diyl bis(4-methylbenzenesulfonate) is a chemical compound with the molecular formula C16H14O6S2. It is a derivative of but-2-yne-1,4-diyl, which is a diyne with two carbon-carbon triple bonds, and is bisulfonated with 4-methylbenzenesulfonate groups. but-2-yne-1,4-diyl bis(4-methylbenzenesulfonate) is characterized by its linear structure, with two 4-methylbenzenesulfonate groups attached to the terminal carbon atoms of the but-2-yne-1,4-diyl backbone. It is an organic compound that can be used in various chemical reactions and synthesis processes, particularly in the preparation of polymers and other organic materials. Due to its specific structure, it may exhibit unique chemical properties and reactivity, making it a potentially valuable intermediate in the synthesis of more complex molecules.

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  • 1-methyl-4-[4-(4-methylphenyl)sulfonyloxybut-2-ynoxysulfonyl]benzene

    Cas No: 6337-59-3

  • USD $ 1.9-2.9 / Gram

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  • 6337-59-3 Structure
  • Basic information

    1. Product Name: but-2-yne-1,4-diyl bis(4-methylbenzenesulfonate)
    2. Synonyms:
    3. CAS NO:6337-59-3
    4. Molecular Formula: C18H18O6S2
    5. Molecular Weight: 394.4619
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 6337-59-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 576°C at 760 mmHg
    3. Flash Point: 302.2°C
    4. Appearance: N/A
    5. Density: 1.334g/cm3
    6. Vapor Pressure: 1.14E-12mmHg at 25°C
    7. Refractive Index: 1.58
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: but-2-yne-1,4-diyl bis(4-methylbenzenesulfonate)(CAS DataBase Reference)
    11. NIST Chemistry Reference: but-2-yne-1,4-diyl bis(4-methylbenzenesulfonate)(6337-59-3)
    12. EPA Substance Registry System: but-2-yne-1,4-diyl bis(4-methylbenzenesulfonate)(6337-59-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 6337-59-3(Hazardous Substances Data)

6337-59-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6337-59-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,3 and 7 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 6337-59:
(6*6)+(5*3)+(4*3)+(3*7)+(2*5)+(1*9)=103
103 % 10 = 3
So 6337-59-3 is a valid CAS Registry Number.

6337-59-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(4-methylphenyl)sulfonyloxybut-2-ynyl 4-methylbenzenesulfonate

1.2 Other means of identification

Product number -
Other names 2-butyne-1,4-diol ditosylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6337-59-3 SDS

6337-59-3Relevant articles and documents

Crosslinked Internal Alkyne-Based Stereo Elastomers: Polymers with Tunable Mechanical Properties

Hsu, Yen-Hao,Dove, Andrew P.,Becker, Matthew L.

, p. 4649 - 4657 (2021/05/29)

New methods to introduce and control polymer network crosslinking and improve mechanical properties of the resulting materials have been investigated extensively. Common methods to enhance the mechanical properties of elastomers include "vulcanization"by

Preparation method of phenylacetic acid

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Paragraph 0036-0037, (2021/02/20)

The invention discloses a preparation method of phenylacetic acid, and relates to the technical field of organic synthesis. The preparation method of phenylacetic acid specifically comprises the following steps of: carrying out sulfonation reaction on alcohol, namely carrying out sulfonation treatment on 2-butyne-1, 4-diol by using p-toluenesulfonyl chloride to obtain a product A; carrying out Friedel-Crafts alkylation reaction, namely reacting benzene with the product A under the catalytic action of a polymerization ionic liquid catalyst to obtain a product B; and oxidizing alkyne, namely, bytaking tetrabutylammonium bromide as PCT and m-CPBA as an oxidizing agent, treating the product B to obtain phenylacetic acid. According to the preparation method of phenylacetic acid provided by theinvention, the prepared phenylacetic acid is high in yield, the operation is simple, the reaction conditions are easy to operate, and the safety is high.

Synthesis and Photodimerization of 2- And 2,3-Disubstituted Anthracenes: Influence of Steric Interactions and London Dispersion on Diastereoselectivity

Geiger, Thomas,Haupt, Anne,Maichle-M?ssmer, C?cilia,Schrenk, Claudio,Schnepf, Andreas,Bettinger, Holger F.

, p. 10120 - 10135 (2019/08/26)

There is increased evidence that the effect of bulky groups in organic, organometallic, and inorganic chemistry is not only repulsive but can be attractive because of London dispersion interactions. The influence of the size of primary alkyl substituents in 2- and 2,3-positions of anthracenes on the diastereoselectivity (anti vs syn dimer) of the [π4s + π4s] photoinduced dimerization is investigated. The synthesis of the anthracene derivatives was achieved by Suzuki-Miyaura reaction of 2,3-dibromoanthracene with alkylboronic acids as well as by reduction of anthraquinones that were obtained from 2,3-disubstituted 1,3-butadienes and naphthoquinone followed by dehydrogenation. The mixtures of dianthracene isomers were analyzed with respect to the anti/syn-ratio of the products by X-ray crystallography and nuclear Overhauser effect spectroscopy. While for the 2,3-dimethylanthracene the anti and syn isomers were formed in equal amounts, the anti dimers are the major products in all other cases. A linear correlation (R2 = 0.98) between the steric size (Charton parameter) and the isomeric ratio suggests that the selectivity is dominated by classical repulsive steric effects. An exception is the iso-butyl substituent that produces an increased amount of the syn isomer. It is suggested that this is due to an exalted effect of London dispersion interactions.

Functionalized and Degradable Polyphthalaldehyde Derivatives

Lutz, J. Patrick,Davydovich, Oleg,Hannigan, Matthew D.,Moore, Jeffrey S.,Zimmerman, Paul M.,McNeil, Anne J.

supporting information, p. 14544 - 14548 (2019/10/02)

Polymers that depolymerize back to monomers can be repeatedly chemically recycled, thereby reducing their environmental impact. Polyphthalaldehyde is a metastable polymer that can rapidly and quantitatively depolymerize due to its low ceiling temperature. However, the effect of substitution on the physical and chemical properties of polyphthalaldehyde derivatives has not been systematically studied. Herein, we investigate the cationic polymerization of seven o-phthalaldehyde derivatives and demonstrate that judicious choice of substituent results in materials with a wide range of ceiling temperatures (-60 to 106 °C) and decomposition temperatures (109-196 °C). We anticipate that these new polymers and their derivatives will enable researchers to access degradable materials with tunable thermal, physical, and chemical properties.

Twisted Cycloalkynes and Remote Activation of “Click” Reactivity

Harris, Trevor,Gomes, Gabriel dos Passos,Ayad, Suliman,Clark, Ronald J.,Lobodin, Vladislav V.,Tuscan, Megan,Hanson, Kenneth,Alabugin, Igor V.

supporting information, p. 629 - 640 (2017/12/07)

The “twisted and bent” cyclodecyne structural motif, intertwined with dormant electronic effects, opens a conceptually powerful way to control “click” reactivity. The endocyclic heteroatoms of cyclodecynes provide dual electronic activation via hyperconju

Diaryl sulfide derivative, preparation method thereof and application thereof as serotonin transporter targeted imaging agent

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Paragraph 0069; 0070, (2017/10/07)

The invention belongs to the field of radiopharmaceutical chemistry and relates to a diaryl sulfide derivative, a preparation method thereof and application thereof as a serotonin transporter targeted imaging agent. The diaryl sulfide derivative has a structural formula shown in the description, exhibits high affinity with central SERT (serotonin transporter) and high selectivity for SERT relative to DAT (dopamine transporter) and NET (norepinephrine transporter). Therefore, the [18F]-diaryl sulfide derivative of the invention may act as an SERT/PET (positron emission tomography) imaging agent.

Synthesis and in vitro characterization of novel fluorinated derivatives of the TSPO 18 kDa ligand SSR180575

Damont, Annelaure,Marguet, Frank,Puech, Frédéric,Dollé, Frédéric

, p. 736 - 745 (2015/08/04)

Abstract SSR180575 (1) is a high-affinity (0.83 nM) TSPO 18 kDa ligand belonging to the pyridazino[4,5-b]indole-1-acetamides family. Herein we describe the synthesis and in vitro characterization of two series of new fluorinated analogues. Eleven compounds (out of fifteen) displayed nanomolar to subnamolar affinities (0.30-8.1 nM) and high selectivities (Ki(CBR)/Ki(TSPO) > 103). Two derivatives stand out as promising candidates for drug development or use as PET probes for in vivo neuroinflammation imaging, once fluorine-18-labelled.

Synthesis, radioiodination and in vivo screening of novel potent iodinated and fluorinated radiotracers as melanoma imaging and therapeutic probes

Maisonial, Aurélie,Billaud, Emilie M.F.,Besse, Sophie,Rbah-Vidal, Latifa,Papon, Janine,Audin, Laurent,Bayle, Martine,Galmier, Marie-Josèphe,Tarrit, Sébastien,Borel, Michèle,Askienazy, Serge,Madelmont, Jean-Claude,Moins, Nicole,Auzeloux, Philippe,Miot-Noirault, Elisabeth,Chezal, Jean-Michel

, p. 840 - 853 (2013/07/27)

In order to develop new iodinated and fluorinated matched-pair radiotracers for Single-Photon Emission Computed Tomography (SPECT)/Positron Emission Tomography (PET) imaging and targeted radionuclide therapy of melanoma, we successfully synthesized and ra

HEPATITIS C INHIBITOR COMPOUNDS

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Page/Page column 38, (2011/06/23)

Compounds of the invention, which are macrocyclic peptide analogs containing an acylsulfonamide moiety, maintain good activity against NS3 proteases containing clinically relevant resistance mutations for this class as represented by genotype 1 a R155K, genotype 1 b D168V and genotype 1 a D168V resistance mutations. The compounds of the invention are useful as inhibitors of HCV NS3 protease for the treatment of hepatitis C viral infection.

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