634180-78-2

Basic information

• Product Name: 3-Cyclopentene-1-carboxylicacid,2-(benzoylamino)-,ethylester,(1R,2S)-rel-
• Synonyms: 3-Cyclopentene-1-carboxylicacid,2-(benzoylamino)-,ethylester,(1R,2S)-rel-
• CAS NO: 634180-78-2
• Molecular Formula: C15H17NO3
• Molecular Weight: 259.30038
• Product Categories: AMIDE
• Mol File: 634180-78-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Cyclopentene-1-carboxylicacid,2-(benzoylamino)-,ethylester,(1R,2S)-rel-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyclopentene-1-carboxylicacid,2-(benzoylamino)-,ethylester,(1R,2S)-rel-(634180-78-2)
• EPA Substance Registry System: 3-Cyclopentene-1-carboxylicacid,2-(benzoylamino)-,ethylester,(1R,2S)-rel-(634180-78-2)

Safety Data

• Hazardous Substances Data: 634180-78-2(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 790657-32-8 C₈H₁₃NO₂ 
• 1006611-38-6 C₈H₁₃NO₂ 
• 1607805-66-2 ethyl (1R,2S)-2-benzamidocyclopent-3-enecarboxylate 
• 63838-48-2 6-Azabicyclo<3.2.0>hept-3-en-7-one 
• 138039-48-2 (+)-(1R,2S)-2-aminocyclopent-3-ene-1-carboxylic acid 
• 146864-12-2 (1S,5R)-6-azabicyclo[3.2.0]hept-3-en-7-one 
• 64-17-5 ethanol 
• 138039-48-2 (+/-)-cis-2-amino-3-cyclopentenecarboxylic acid 

Relevant articles and documents

A de Novo Stereocontrolled Approach to syn- and anti-Disubstituted Acyclic β2,3-Amino Acid Enantiomers

The stereocontrolled syntheses of functionalized acyclic β2,3-amino acid derivatives in enantiomerically pure form were performed by starting from enantiopure cis- and trans-2-aminocyclopent-3-enecarboxylates, which were derived from a racemic bicyclic β-lactam. The synthetic strategy involves the stereoselective dihydroxylaton of the C-C double bond of the cyclopentene β-amino esters. The subsequent NaIO4-mediated ring cleavage affords dialdehyde intermediates that undergo functionalization by a Wittig reaction.

A de Novo stereocontrolled approach to syn- and anti-disubstituted acyclic β2,3-amino acid enantiomers

The stereocontrolled syntheses of functionalized acyclic β2,3-amino acid derivatives in enantiomerically pure form were performed by starting from enantiopure cis- and trans-2-aminocyclopent-3- enecarboxylates, which were derived from a racemic bicyclic β-lactam. The synthetic strategy involves the stereoselective dihydroxylaton of the C-C double bond of the cyclopentene β-amino esters. The subsequent NaIO 4-mediated ring cleavage affords dialdehyde intermediates that undergo functionalization by a Wittig reaction. The stereocontrolled syntheses of functionalized acyclic β2,3-amino acid derivatives in enantiomerically pure form have been performed in five steps by starting from enantiopure cis- and trans-2-aminocyclopent-3-enecarboxylates, which were derived from a racemic bicyclic β-lactam. Copyright

Intramolecular carbolithiation reactions for the preparation of 3-alkenylpyrrolidines.

Tin-lithium exchange allows the formation of alpha-amino-organolithium species that undergo anionic cyclization onto allylic ethers to give 3-alkenylpyrrolidines. The methodology has been applied to the synthesis of an advanced intermediate related to the natural product (-)-alpha-kainic acid.