3-Cyclopentene-1-carboxylicacid,2-(benzoylamino)-,ethylester,(1R,2S)-rel-

Base Information

• Chemical Name: 3-Cyclopentene-1-carboxylicacid,2-(benzoylamino)-,ethylester,(1R,2S)-rel-
• CAS No.: 634180-78-2
• Molecular Formula: C15H17NO3
• Molecular Weight: 259.3
• Mol file: 634180-78-2.mol

Synonyms:3-Cyclopentene-1-carboxylicacid,2-(benzoylamino)-,ethylester,(1R,2S)-rel-

Chemical Property of 3-Cyclopentene-1-carboxylicacid,2-(benzoylamino)-,ethylester,(1R,2S)-rel-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Cyclopentene-1-carboxylicacid,2-(benzoylamino)-,ethylester,(1R,2S)-rel-

There total 18 articles about 3-Cyclopentene-1-carboxylicacid,2-(benzoylamino)-,ethylester,(1R,2S)-rel- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

benzoyl chloride (98-88-4) + (1SR,2RS)-ethyl 2-aminocyclopent-3-enecarboxylate hydrochloride → (1SR,2RS)-ethyl 2-(benzoylamino)cyclopent-3-enecarboxylate (634180-78-2)

Guidance literature:

With triethylamine; In diethyl ether; at 0 ℃; for 18h;

DOI:10.1039/b303670g

Reference yield: 81.0%

ethanol (64-17-5) + benzoyl chloride (98-88-4) + (+)-(1R,2S)-2-aminocyclopent-3-ene-1-carboxylic acid (138039-48-2,154568-20-4,122022-98-4) → ethyl (1R,2S)-2-benzamidocyclopent-3-enecarboxylate (1607805-66-2,634180-78-2)

Guidance literature:

ethanol; (+)-(1R,2S)-2-aminocyclopent-3-ene-1-carboxylic acid; With thionyl chloride;

benzoyl chloride; With sodium hydroxide; In water; toluene; at 0 ℃; for 1h;

DOI:10.1002/ejoc.201301281

Reference yield: 76.0%

ethyl (1R,2S)-2-benzamidocyclopent-3-enecarboxylate (1607805-66-2,634180-78-2) → ethyl (1S,2S)-2-benzamidocyclopent-3-enecarboxylate (1607805-67-3,634180-78-2)

Guidance literature:

With sodium ethanolate; In ethanol; at 0 ℃; for 12h;

DOI:10.1002/ejoc.201301281 DOI:10.1002/ejoc.201301281

upstream raw materials:

benzoyl chloride

ethanol

(+/-)-cis-2-amino-3-cyclopentenecarboxylic acid

C₈H₁₃NO₂