654680-82-7

Basic information

• Product Name: (1R,3R,4S,6S)-4-AMINO-4,7,7-TRIMETHYL-BICYCLO[4.1.0]HEPT-3-YL-METHANOL
• Synonyms: (1R,3R,4S,6S)-4-AMINO-4,7,7-TRIMETHYL-BICYCLO[4.1.0]HEPT-3-YL-METHANOL
• CAS NO: 654680-82-7
• Molecular Formula: C₁₁H₂₁NO
• Molecular Weight: 183.29
• Mol File: 654680-82-7.mol

Chemical Properties

• Boiling Point: 257.5°C at 760 mmHg
• Flash Point: 109.6°C
• Appearance: /
• Density: 0.973g/cm³
• Vapor Pressure: 0.00215mmHg at 25°C
• Refractive Index: 1.486
• CAS DataBase Reference: (1R,3R,4S,6S)-4-AMINO-4,7,7-TRIMETHYL-BICYCLO[4.1.0]HEPT-3-YL-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3R,4S,6S)-4-AMINO-4,7,7-TRIMETHYL-BICYCLO[4.1.0]HEPT-3-YL-METHANOL(654680-82-7)
• EPA Substance Registry System: (1R,3R,4S,6S)-4-AMINO-4,7,7-TRIMETHYL-BICYCLO[4.1.0]HEPT-3-YL-METHANOL(654680-82-7)

Safety Data

• Hazardous Substances Data: 654680-82-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(1R,3R,4S,6S)-4-AMINO-4,7,7-TRIMETHYL-BICYCLO[4.1.0]HEPT-3-YL-METHANOL is used as a potential pharmaceutical candidate for various applications due to its unique structure and functional groups. Its potential uses may include the development of new drugs or therapies, targeting specific diseases or conditions. Further research is needed to fully understand its properties and potential applications in the pharmaceutical industry.

InChI:InChI=1/C11H21NO/c1-10(2)8-4-7(6-13)11(3,12)5-9(8)10/h7-9,13H,4-6,12H2,1-3H3/t7-,8+,9-,11-/m0/s1

Upstream product

• 654680-62-3 (1R,3R,4S,6S)-4-tert-butoxycarbonylamino-4,7,7-trimethylbicyclo[4.1.0]heptane-3-carboxylic acid 
• 654680-67-8 methyl (1R,3R,4S,6S)-4-(tert-butoxycarbonylamino)-4,7,7-trimethylbicyclo[4.1.0]heptane-3-carboxylate 
• 654680-57-6 tert-butyl (1R,3R,5S,7S)-4,4,7-trimethyl-9-oxo-8-azatricyclo[5.2.0.0^3,5]nonane-8-carboxylate 
• 655236-18-3 (1R,3R,5S,7S)-4,4,7-trimethyl-8-azatricyclo[5.2.0.0^3,5]nonan-9-one 
• 654680-77-0 methyl (1R,3R,4S,6S)-4-amino-4,7,7-trimethylbicyclo[4.1.0]heptane-3-carboxylate 
• 498-15-7 (+)-Δ³-carene 

Downstream Products

• 1202238-15-0 2,4-di(tert-butyl)-6-{[(1S,3S,4R,6R)-4-hydroxymethyl-3,7,7-trimethylbicyclo[4.1.0]hept-3-ylimino]methyl}phenol 
• 654681-11-5 (1S,3S,4R,6R)-1-(4-hydroxymethyl-3,7,7-trimethylbicyclo[4.1.0]hept-3-yl)-3-phenylthiourea 

Relevant articles and documents

Synthesis of new chiral schiff bases from (+)-3-carene and their use in asymmetric oxidation of sulfides catalyzed by metal complexes

A number of new chiral Schiff bases were synthesized starting from accessible monoterpene (+)-3-carene, and the products were used as ligands in metal complex-catalyzed oxidation of sulfides to chiral sulfoxides. The optical purity and the sign of optical rotation of chiral sulfoxides were found to strongly depend on the oxidation temperature. Pleiades Publishing, Ltd., 2009.

Synthesis and transformation of novel cyclic β-amino acid derivatives from (+)-3-carene

The regio- and stereoselective addition of chlorosulfonyl isocyanate to (+)-3-carene 1 resulted in β-lactam 2, which was converted to N-Boc-β-amino acid 4, β-amino ester 7, and carboxamide derivatives 18 and 20 via N-Boc activation and mild ring opening.