655-63-0

Basic information

• Product Name: α,α-Dibromo-o-tolunitrile
• Synonyms: 2-(Dibromomethyl)benzonitrile;o-Cyanobenzal bromide;o-Cyanobezylidene bromide;α,α-Dibromo-o-tolunitrile
• CAS NO: 655-63-0
• Molecular Formula: C₈H₅Br₂N
• Molecular Weight: 274.94
• Mol File: 655-63-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: α,α-Dibromo-o-tolunitrile(CAS DataBase Reference)
• NIST Chemistry Reference: α,α-Dibromo-o-tolunitrile(655-63-0)
• EPA Substance Registry System: α,α-Dibromo-o-tolunitrile(655-63-0)

Safety Data

• Hazardous Substances Data: 655-63-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
α,α-Dibromo-o-tolunitrile is used as an impurity in the production of Alogliptin, an oral antihyperglycemic agent, for the management of type 2 diabetes. Its presence, although as an impurity, is significant in the pharmaceutical industry due to its association with the production of a drug that helps regulate blood sugar levels in diabetic patients.
As an Antidiabetic Agent:
While α,α-Dibromo-o-tolunitrile itself may not have direct applications as an antidiabetic agent, its connection to Alogliptin, a selective DPP-4 inhibitor, highlights its importance in the development and production of medications aimed at treating type 2 diabetes. DPP-4 inhibitors like Alogliptin work by increasing the levels of insulin-producing hormones, thus helping to lower blood sugar levels in patients with diabetes.

Upstream product

• 529-19-1 2-Methylbenzonitrile 

Downstream Products

• 7468-67-9 o-formylbenzonitrile 
• 119-67-5 o-carboxybenzaldehyde 
• 6306-97-4 1,3-bis(4-methoxyphenyl)isobenzofuran 
• 6335-81-5 2-[(4-bromo-phenylhydrazono)-methyl]-benzonitrile 
• 412025-73-1 2-(α-hydroxy-benzyl)-benzophenone-imine 

Relevant articles and documents

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