6306-97-4

Usage

Class

Isobenzofuran derivatives

Core structure

Isobenzofuran

Substituents

Two 4-methoxyphenyl groups

Attachment positions

1 and 3

Potential applications

a. Photochemical reagent
b. Scaffold for drug design

Biological activities

Studied for potential applications

Research and development

Valuable for pharmaceutical and material science industries

Unique structure

Contributes to its properties and potential uses

InChI:InChI=1/C22H18O3/c1-23-17-11-7-15(8-12-17)21-19-5-3-4-6-20(19)22(25-21)16-9-13-18(24-2)14-10-16/h3-14H,1-2H3

Upstream product

• 21615-74-7 3-(4-methoxyphenyl)phthalide 
• 112219-63-3 (4-methoxyphenyl)magnesium iodide 
• 7468-67-9 o-formylbenzonitrile 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 7664-93-9 sulfuric acid 
• 7477-32-9 acide (dimethoxy-4'4 diphenylmethyl)-2 benzoique 
• 4122-57-0 3-methoxy-3H-isobenzofuran-1-one 
• 4122-56-9 methyl o-formylbenzoate 
• 529-19-1 2-Methylbenzonitrile 
• 15331-49-4 trans-1,2-di(4-methoxybenzoyl)ethylene 
• 74322-73-9 [2-Diethylamino-6-(4-methoxy-benzoyl)-cyclohex-3-enyl]-(4-methoxy-phenyl)-methanone 
• 108-24-7 acetic anhydride 
• 5435-44-9 (E)-3-Ureido-but-2-enoic acid ethyl ester 
• 655-63-0 2-(dibromomethyl)benzonitrile 

Downstream Products

• 95793-17-2 {2-[2,2-Dichloro-1-(4-methoxy-phenyl)-vinyl]-phenyl}-(4-methoxy-phenyl)-methanone 
• 5441-28-1 1,4-bis-(4-methoxy-phenyl)-phthalazine 
• 855422-65-0 1,2-bis-(4-hydroxy-benzoyl)-benzene 
• 860531-53-9 2-methoxy-9-(4-methoxyphenyl)anthracene 
• 7477-30-7 1,2-bis-(α-hydroxyimino-4-methoxy-benzyl)-benzene 
• 1054569-40-2 1,3-bis(4-methoxyphenyl)benzo[c]selenophene 
• 1610619-66-3 5,13-bis(4-methoxyphenyl)-6,11-diphenyl-12H-dibenzo[b,h]fluoren-12-one 
• 1610619-69-6 5,6,11,13-tetrakis(4-methoxyphenyl)-12H-dibenzo[b,h]fluoren-12-one 
• 1610619-89-0 C₂₇H₂₂O₃ 
• 1610619-75-4 C₆₆H₆₂O₁₀S₂ 
• 1610619-79-8 C₇₈H₈₆O₁₀S₂ 
• 1610619-86-7 C₇₂H₆₅NO₈S₂ 
• 1610619-51-6 5,13-bis(4-methoxyphenyl)dinaphtho[2,3-b:2',3'-d]thiophene S,S-dioxide 
• 1610619-49-2 6,11-bis(4-methoxyphenyl)benzo[b]naphtho[2,3-d]thiophene S,S-dioxide 

Relevant academic research and scientific papers

A One-pot preparation of 1,3-diarylisobenzofuran

A simple, practical, and efficient method for one-pot synthesis of symmetric and unsymmetrical 1,3-diarylisobenzofurans has been developed by sequential reactions of methyl 2-formylbenzoate with two identical or different aryl metal species.

Synthesis and characterization of 1,3-diarylbenzo[c]selenophenes

A series of 1,3-diarylbenzo[c]selenophenes (symmetrical/unsymmetrical) have been synthesized involving a selenium transfer reaction of keto-alcohol/benzo[c]furan using Woollins reagent. The optical and electrochemical studies of these diarylbenzo[c]selenophenes are correlated with their structures.

A single-step synthesis of symmetrical 1,3-diarylisobenzofurans

A convenient single-step synthesis of various symmetrically substituted 1,3-diarylisobenzofurans from readily available 3-methoxy-3H-isobenzofuran-1-one (1a) and two equivalents of aryl Grignard reagents is described. The title compounds are obtained in medium to high isolated yields. Crude isobenzofuran has also been trapped by maleimide, furnishing pure Diels-Alder adduct almost quantitatively. Georg Thieme Verlag Stuttgart.