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N-diphenylacetylglycine is a chemical compound with the molecular formula C18H15NO2. It is a derivative of acetylglycine, an amino acid derivative. N-diphenylacetylglycine is known for its ability to form stable and soluble complexes with metal ions, making it a versatile ligand in coordination chemistry and a valuable building block in organic synthesis. Its applications extend to the pharmaceutical industry, where it serves as a raw material for synthesizing various pharmaceutical compounds. Furthermore, N-diphenylacetylglycine has been investigated for its potential biological activities, including anti-inflammatory and analgesic effects.

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  • 65707-74-6 Structure
  • Basic information

    1. Product Name: N-diphenylacetylglycine
    2. Synonyms: Glycine, N-(2,2-diphenylacetyl)-; Glycine, N-(diphenylacetyl)-; N-(Diphenylacetyl)glycine
    3. CAS NO:65707-74-6
    4. Molecular Formula: C16H15NO3
    5. Molecular Weight: 269.3
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 65707-74-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 541.6°Cat760mmHg
    3. Flash Point: 281.4°C
    4. Appearance: /
    5. Density: 1.225g/cm3
    6. Vapor Pressure: 1.45E-12mmHg at 25°C
    7. Refractive Index: 1.595
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: N-diphenylacetylglycine(CAS DataBase Reference)
    11. NIST Chemistry Reference: N-diphenylacetylglycine(65707-74-6)
    12. EPA Substance Registry System: N-diphenylacetylglycine(65707-74-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 65707-74-6(Hazardous Substances Data)

65707-74-6 Usage

Uses

Used in Coordination Chemistry:
N-diphenylacetylglycine is used as a ligand for forming stable and soluble complexes with metal ions. This property makes it useful in catalytic reactions and as a chelating agent, contributing to advancements in this scientific field.
Used in Organic Synthesis:
As a building block in organic synthesis, N-diphenylacetylglycine aids in the creation of various complex organic compounds, further expanding its utility in chemical research and development.
Used in Pharmaceutical Industry:
N-diphenylacetylglycine is utilized as a raw material in the synthesis of a range of pharmaceutical compounds, highlighting its importance in drug development and production.
Used in Biological Research:
N-diphenylacetylglycine has been studied for its potential biological activities such as anti-inflammatory and analgesic effects, indicating its possible use in the development of new therapeutic agents for treating inflammation and pain.

Check Digit Verification of cas no

The CAS Registry Mumber 65707-74-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,7,0 and 7 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 65707-74:
(7*6)+(6*5)+(5*7)+(4*0)+(3*7)+(2*7)+(1*4)=146
146 % 10 = 6
So 65707-74-6 is a valid CAS Registry Number.
InChI:InChI=1/C16H15NO3/c18-14(19)11-17-16(20)15(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10,15H,11H2,(H,17,20)(H,18,19)

65707-74-6Relevant articles and documents

Controlled submolecular translational motion in synthesis: A mechanically interlocking auxiliary

Hannam, Jeffrey S.,Lacy, Stephen M.,Leigh, David A.,Saiz, Carlos G.,Slawin, Alexandra M. Z.,Stitchell, Sheila G.

, p. 3260 - 3264 (2007/10/03)

Sew simple: How can you put a molecular bead on a thread when no recognition elements exist between them? A mechanically interlocking auxiliary assembles the macrocycle around a template, controlled submolecular translation moves the ring over the desired

Composition containing a penem or carbapenem antibiotic and the use of the same

-

, (2008/06/13)

Administration of an N-acylated amino acid in association with a penem or carbapenem antibiotic relieves or eliminates the renal problems associated with administration of the antibiotic alone. The amino acid derivative and antibiotic may be formulated together as a composition or administered separately, either simultaneously or sequentially.

Composition containing a penem or carbapenem antibiotic

-

, (2008/06/13)

Administration of an N-acylated amino acid in association with a penem or carbapenem antibiotic relieves or eliminates the renal problems associated with administration of the antibiotic alone. The amino acid derivative and antibiotic may be formulated together as a composition or administered separately, either simultaneously or sequentially. The composition may be prepared by simple mixing.

Use of 2-pyrimidine thiol carbonates as acylating agents for amino or imino containing compounds

-

, (2008/06/13)

Thiolcarbonates represented by the formula, SPC1 Wherein R1 and R2 are individually a hydrogen atom or a methyl group, and R3 is a straight chain or branched chain saturated or unsaturated alkyl group having 1 to 5 carbon atoms or is a benzyl or benzhydryl group which may be nuclear substituted, are quite useful for protecting the amino or imino groups of amines, hydrazines, amino acids and peptides with groups of the formula EQU1 The thiolcarbonates can be easily produced by reacting an alkali metal salt of 2-mercaptopyrimidine with phosgene, and reacting the resulting thiolchloroformate with an alcohol (R3 OH), or by reacting a 2-mercaptopyrimidine with a halocarbonic acid ester.

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