65922-85-2

Basic information

• Product Name: 5-METHYL-MORPHOLIN-3-ONE
• Synonyms: 5-METHYL-MORPHOLIN-3-ONE;5-METHYL-3-MORPHOLINONE;5-methyl-3-morpholinone(SALTDATA: FREE)
• CAS NO: 65922-85-2
• Molecular Formula: C5H9NO2
• Molecular Weight: 115.13046
• Mol File: 65922-85-2.mol

Chemical Properties

• Melting Point: 32-34 °C(Solv: pentane (109-66-0))
• Boiling Point: 290.9°C at 760 mmHg
• Flash Point: 129.8°C
• Appearance: /
• Density: 1.046g/cm³
• Vapor Pressure: 0.00201mmHg at 25°C
• Refractive Index: 1.426
• PKA: 14.43±0.40(Predicted)
• CAS DataBase Reference: 5-METHYL-MORPHOLIN-3-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-METHYL-MORPHOLIN-3-ONE(65922-85-2)
• EPA Substance Registry System: 5-METHYL-MORPHOLIN-3-ONE(65922-85-2)

Safety Data

• Hazardous Substances Data: 65922-85-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H9NO2/c1-4-2-8-3-5(7)6-4/h4H,2-3H2,1H3,(H,6,7)

Upstream product

• 119907-19-6 2-chloro-N-(1-hydroxypropan-2-yl)acetamide 
• 6168-72-5 2-Amino-1-propanol 
• 10294-56-1 phosphorous acid 
• 2749-11-3 (S)-Alaninol 
• 105-39-5 chloroacetic acid ethyl ester 

Downstream Products

• 42185-06-8 3-methylmorpholine 

Relevant articles and documents

A concise and efficient synthesis of substituted morpholines

A simple and efficient method has been developed for the synthesis of substituted morpholines by a sequence of coupling, cyclization, and reduction reactions of easily available amino alcohols and α-halo acid chlorides. Various mono-, di-, and trisubstituted morpholines, spiro morpholines, and ring-fused morpholines, as well as morpholine homologues, were synthesized in good to excellent yields by a single methodology under similar reaction conditions. The method was also used in a multigram synthesis of (3S)-3-methylmorpholine.

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