cas 66336-02-5, 1-ethyl-5-nitropyridin-2(1H)-one

Articles about 66336-02-5Total 6 be found

COMPOUNDS AND USES THEREOF
The present invention features compounds useful in the treatment of neurological disorders and primary brain cancer. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders and primary brain cancer.
-
Page/Page column 193; 194

(2020/10/20)

COMPOUNDS AND USES THEREOF
The present invention features compounds useful in the treatment of neurological disorders. The compounds of the invention, alone or in combination with other pharmaceutically active agents, can be used for treating or preventing neurological disorders.
-
Page/Page column 187-188

(2019/10/15)

SUBSTITUTED PYRIDAZINE CARBOXAMIDE COMPOUNDS AS KINASE INHIBITOR COMPOUNDS
The new pyridazine derivatives have unexpected drug properties as inhibitors of protein kinases especially against c-Met and are useful in treating disorders related to abnormal protein kinase activities such as cancer.
-
Page/Page column 36

(2012/04/23)

Microwave assisted rapid preparation of N-alkyl-2-pyridones under neutral conditions by Hilbert-Johnson reaction
The reactions of 2-methoxypyridine with haloalkanes without solvent and catalyst under microwave irradiation (100-200 °C, 5 min) yielded the corresponding N-alkyl-2(1H)-pyridones in good to moderate yields. However, the reactions were sensitive to length of haloalkanes. In contrast, the reactions of 2-alkoxypyridines with corresponding iodoalkanes under microwave irradiation (150 °C) proceeded rapidly without catalyst and solvent, and were complete within 5 min to afford N-alkyl-2(1H)-pyridones in good to excellent yields. The Japan Institute of Heterocyclic Chemistry.
Iida, Hirokazu,Suda, Machiko,Nakajima, Etsuko,Hakamatsuka, Hiroko,Nagashima, Yuka,Joho, Kouta,Amemiya, Kenta,Moromizato, Tatsuya,Matsumoto, Kiyoshi,Murakami, Yasuoki,Hamana, Hiroshi
scheme or table
p. 2057 - 2062
(2011/04/12)

SUBSTITUTED PYRIDAZINE CARBOXAMIDE COMPOUNDS AS KINASE INHIBITOR COMPOUNDS
Pyridazine derivatives have unexpected drug properties as inhibitors of protein kinases and are useful in treating disorders related to abnormal protein kinase activities such as cancer.
-
Page/Page column 51

(2010/01/12)

Hilbert-Johnson reaction under high pressure: A facile preparation of 2-pyridones
For the first time, a facile synthesis of 2-pyridones utilizing a classical Hilbert-Johnson reaction of 2-methoxypyridines with haloalkanes under high pressure has been achieved. The reactions were sensitive to steric hindrance of haloalkanes.
Matsumoto, Kiyoshi,Ikemi, Yukio,Suda, Machiko,Iida, Hirokazu,Hamana, Hiroshi
p. 187 - 190
(2008/03/12)