667420-92-0Relevant articles and documents
The mechanism of the zirconium catalysed ethyl- and 2-magnesioethyl-magnesiation of unactivated alkenes
Lewis,Lewis, Dorian P.,Whitby,Whitby, Richard J.,Jones,Jones, Raymond V. H.
, p. 4541 - 4550 (1995)
Deuterium labelling experiments prove that the zirconocene dichloride catalysed ethylmagnesiation of alkenes occurs via a zirconocene η2-ethylene complex and allow a deuterium isotope effect for a key β-hydride transfer to be estimated (k(H)/k(D) = 2.5). Transmetallation from zirconium to magnesium to form 1,4-dimagnesiated reagents is shown to be an intramolecular process. Kinetic studies show that the reaction between η2-ethylene zirconocene and the alkene is rate limiting and that Lewis bases inhibit the reaction by decreasing the amount of η2-ethylene zirconocene in equilibrium with the 'ate' complex [Cp2Zr(CH2=CH2)Et]-.[MgX.Base]+.
Catalytic hydrogenation of amides to amines under mild conditions
Stein, Mario,Breit, Bernhard
supporting information, p. 2231 - 2234 (2013/03/28)
Under (not so much) pressure: A general method for the hydrogenation of tertiary and secondary amides to amines with excellent selectivity using a bimetallic Pd-Re catalyst has been developed. The reaction proceeds under low pressure and comparatively low temperature. This method provides organic chemists with a simple and reliable tool for the synthesis of amines. Copyright
Isoprene hydroamination catalyzed by palladium xantphos complexes
Tamaddoni Jahromi, Bahareh,Nemati Kharat, Ali,Zamanian, Sara,Bakhoda, Abolghasem,Mashayekh, Kobra,Khazaeli, Sadegh
experimental part, p. 188 - 196 (2012/09/07)
Pd(II) Xantphos or Xantphos chalcogenide complexes with general folmula [PdCl2(X∩X)] (where X = P, O, S or Se) were synthesized by the addition of corresponding ligands to [PdCl2(COD)] (COD = 1,5-cyclooctadiene). Prepared Complexes [
A Zirconium Catalysed Synthesis of 1,4-Dimagnesium Reagents.
Lewis, Dorian P.,Muller, Philippe M.,Whitby, Richard J.,Jones, Raymond V. H.
, p. 6797 - 6800 (2007/10/02)
The zirconium catalysed addition of diethylmagnesium to a variety of unactivated alkenes affords either the simple carbometallation product, or 1,4-dimagnesium reagents depending on the conditions and substrate.The products can be successfully functionalised with a variety of electrophiles.Key Words: Zirconium; Grignard; Carbometallation; 1,4-Dimagnesium; Catalysis.
