- Lightening Agents and/or Dyes that Contain Aldehyde(s)
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Agents for dyeing and/or lightening keratin fibers, in particular human hair, containing, relative to the weight thereof, 0.001 to 15 wt. % of at least one aldehyde of the formula (I): wherein X represents —CH(R2)—SO2—Y—R1, —CR3R4R5, or wherein Y represents —CH(CHO)— or —CH2— or a chemical bond, and wherein each of R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 independently represents —H or —CN or —F or —Cl or —Br or —I or —CHO or —NH2 or —NO2 or —CF3 or —CCl3 or —CF2CF3 or —CCl2CCl3 or an optionally substituted (C1-C6) alkyl group or a hydroxyalkyl group or a polyhydroxyalkyl group or an optionally substituted (C1-C6) alkylene group, and wherein the agent contains no oxidation dye precursors of developer and coupler type.
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- Imaging of Enzyme Activity
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This invention relates to biochemistry and magnetic resonance imaging.
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- Imaging thrombus with glycoprotein llb/llla antagonists
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This invention relates to a method of using a radiolabeled small molecule antagonist of the platelet IIb/IIIa receptor for the diagnosis of arterial and venous thrombi.
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- Process for producing an amide compound
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There is disclosed a process for producing an amide compound, which process is characterized in that a compound having an amino group are reacted with a polyaminopolycarboxylic acid anhydride in the presence of the polyaminopolycarboxylic acid.
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- Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging
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This invention relates to a method of using radiolabelled and/or radiopharmaceutical small molecule inhibitors of beta-amyloid peptide production for the diagnosis of neurological and other disorders involving APP processing and beta-amyloid production. Furthermore, radiolabelled small molecule inhibitors identified by the methods of the present invention would be useful in the diagnosis of neurological disorders, such as Alzheimer's disease, which involve elevated levels of Aβ peptides.
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- Polypeptide derivatives
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A biologically active peptide selected from growth factors, peptide hormones, interferons and cytokines and analogues and derivatives thereof, and bearing at least one chelating group linked to an amino group of said peptide, the chelating group being capable of complexing a detectable element and such amino group having no significant binding affinity to target receptors, are complexed with a detectable element and are useful as a pharmaceutical, e.g. a radiopharmaceutical for in vivo imaging of target tissues or for therapy.
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- Water-soluble Hexadentate Schiff-base Ligands as Sequestrating Agents for Iron(III) and Gallium(III)
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Complexes of FeIII and GaIII with hexadentate Schiff-base ligands have been characterised in aqueous solution.They were prepared by the condensation of salicylaldehydes, containing a sulphonate or trimethylammonium group, with polyamines in the presence of the metal ions.These complexes have stabilities, at physiological pH, similar to those of the hydroxamic acid siderophore complexes.The kinetics of the displacement of FeIII from III(edta)>(1-) (edta = ethylenediamine-N,N,N',N'-tetra-acetate) by two of these ligands has been studied.
- Evans, Dennis F.,Jakubovic, David A.
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p. 2927 - 2934
(2007/10/02)
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