67285-54-5

Basic information

• Product Name: Benzene, 1-(hexyloxy)-2-nitro-
• CAS NO: 67285-54-5
• Molecular Formula: C12H17NO3
• Molecular Weight: 223.272
• Mol File: 67285-54-5.mol

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(hexyloxy)-2-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(hexyloxy)-2-nitro-(67285-54-5)
• EPA Substance Registry System: Benzene, 1-(hexyloxy)-2-nitro-(67285-54-5)

Safety Data

• Hazardous Substances Data: 67285-54-5(Hazardous Substances Data)

Upstream product

• 111-25-1 1-bromo-hexane 
• 88-75-5 2-hydroxynitrobenzene 
• 80033-60-9 tert-butyldimethyl(n-hexyloxy)silane 
• 1493-27-2 ortho-nitrofluorobenzene 
• 111-27-3 hexan-1-ol 
• 86255-27-8 silver(I) 2-nitrophenoxide 
• 638-45-9 1-Iodohexane 
• 3839-35-8 4-methylbenzenesulfonic acid n-hexylester 
• 824-39-5 sodium o-nitrophenate 

Downstream Products

• 98771-65-4 2-(2-Hexyloxy-phenylamino)-6-oxo-1,6-dihydro-pyrimidine-5-carboxylic acid ethyl ester 
• 98772-17-9 2-(2-Hexyloxy-phenylamino)-6-oxo-1,6-dihydro-pyrimidine-5-carboxylic acid 
• 52464-50-3 2-(hexyloxy)aniline 

Relevant articles and documents

AMINE COMPOUNDS HAVING ANTI-INFLAMMATORY, ANTIFUNGAL, ANTIPARASITIC AND ANTICANCER ACTIVITY

Amine compounds having activity against inflammation, fungi, unicellular parasitic microorganisms, and cancer are described. The compounds contain a monocyclic, bicyclic, or tricyclic aromatic ring having one, two, or three ring nitrogen atoms.

Nucleophilic aromatic substitution using Et3SiH/cat. t-Bu-P4 as a system for nucleophile activation

A novel type of deprotonative arylation of nucleophiles was conducted using Et3SiH/cat. t-Bu-P4 and the powerful SNAr reactions of aryl fluorides were accomplished using alcohols and malonates as nucleophiles. The Royal Society of Ch

Catalytic activation of silylated nucleophiles using tBu-P4 as a base

Trialkylsilyl groups play an important role as effective protecting groups in organic synthesis. Various O, N, and C nucleophilic sites can be protected by trialkylsilyl groups to control the selectivity of reactions. The nucleophilic attack of a fluoride anion on a silyl group is recognized as one of the most useful methods for desilylation. The activation of the nucleophile-silicon bond is important not only for desilylation but also for the generation of a reactive nucleophilic anion to achieve a new bond formation. The phosphazene bases developed by Schwesinger are known to be strong non-metallic organic bases. Among them, the tBu-P4 base has been used for various selective deprotonative transformations, although the ability of tBu-P4 base to activate silylated nucleophiles has not yet been shown. A novel catalytic activation of various O, N, and C nucleophile-silicon bonds using tBu-P4 base was investigated to perform nucleophilic reactions with various electrophiles. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.