674793-50-1

Basic information

• Product Name: Methyl 4-{[2-(5-chloro-2-fluorophenyl)-5-methoxypyrimidin-4-yl]amino}nicotinate
• Synonyms: Methyl 4-{[2-(5-chloro-2-fluorophenyl)-5-methoxypyrimidin-4-yl]amino}nicotinate;Methyl 4-{[2-(5-Chloro-2-fluorophenyl)-5-methoxypyrimidin-4-
• CAS NO: 674793-50-1
• Molecular Formula: C18H14ClFN4O3
• Molecular Weight: 388.7801632
• Mol File: 674793-50-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Methyl 4-{[2-(5-chloro-2-fluorophenyl)-5-methoxypyrimidin-4-yl]amino}nicotinate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-{[2-(5-chloro-2-fluorophenyl)-5-methoxypyrimidin-4-yl]amino}nicotinate(674793-50-1)
• EPA Substance Registry System: Methyl 4-{[2-(5-chloro-2-fluorophenyl)-5-methoxypyrimidin-4-yl]amino}nicotinate(674793-50-1)

Safety Data

• Hazardous Substances Data: 674793-50-1(Hazardous Substances Data)

Upstream product

• 674793-47-6 C₁₁H₇Cl₂FN₂O 
• 16135-36-7 methyl 4-aminonicotinate 

Relevant articles and documents

CARBOXAMIDE 4-[(4-PYRIDYL)AMINO]PYRIMIDINES USEFUL AS HCV INHIBITORS

The present invention relates to the use of carboxamide 4-[(4-pyridyl)amino]- pyrimidines as inhibitors of HCV replication as well as their use in pharmaceutical compositions aimed to treat or combat HCV infections.

CARBOXAMIDE INHIBITORS OF TGFB

Certain appropriately substituted forms of pyrimidine having a pyridylamine group at C- 4 of the pyrimidine and an amide group on the pyridine ring are useful in the treatment of conditions associated with excessive TGFB activity.

INHIBITORS OF TFGβ

Certain appropriately substituted forms of pyrimidine and triazine are useful in the treatment to conditions associated with enhanced TGFβ activity.