675109-37-2

Basic information

• Product Name: 6-BROMO-N-METHYLPYRID-2-YLMETHYLAMINE
• Synonyms: 6-BROMO-N-METHYLPYRID-2-YLMETHYLAMINE;(6-Bromo-pyridin-2-ylmethyl)-methyl-amine;1-(6-Bromopyridin-2-yl)-N-methylmethanamine;(6-Bromo-1-methyl-1,6-dihydropyridin-2-yl)methanamine
• CAS NO: 675109-37-2
• Molecular Formula: C₇H₉BrN₂
• Molecular Weight: 201.07
• Mol File: 675109-37-2.mol

Chemical Properties

• Boiling Point: 249.8°C at 760 mmHg
• Flash Point: 104.9°C
• Appearance: /
• Density: 1.431g/cm³
• Vapor Pressure: 0.0225mmHg at 25°C
• Refractive Index: 1.556
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 6-BROMO-N-METHYLPYRID-2-YLMETHYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-BROMO-N-METHYLPYRID-2-YLMETHYLAMINE(675109-37-2)
• EPA Substance Registry System: 6-BROMO-N-METHYLPYRID-2-YLMETHYLAMINE(675109-37-2)

Safety Data

• Hazardous Substances Data: 675109-37-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
6-BROMO-N-METHYLPYRID-2-YLMETHYLAMINE is used as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the preparation of diverse chemical compounds, contributing to the development of new medications.
Used in Agrochemical Industry:
6-BROMO-N-METHYLPYRID-2-YLMETHYLAMINE is also utilized as an intermediate in the synthesis of agrochemicals. Its role in the production of these chemicals helps to create effective products for agricultural applications.
Used in Organic Material Production:
6-BROMO-N-METHYLPYRID-2-YLMETHYLAMINE is used in the production of organic materials, where its distinctive properties contribute to the creation of innovative and useful products.
Used in Medicinal Chemistry Research:
Due to its unique structural properties, 6-BROMO-N-METHYLPYRID-2-YLMETHYLAMINE serves as a valuable building block in medicinal chemistry research. It aids scientists in exploring new avenues for drug discovery and the development of novel therapeutic agents.

InChI:InChI=1/C7H9BrN2/c1-9-5-6-3-2-4-7(8)10-6/h2-4,9H,5H2,1H3

Upstream product

• 34160-40-2 6-bromo-2-pyridinecarbaldehyde 
• 74-89-5 methylamine 

Downstream Products

• 1269615-54-4 tert-butyl (2R,5S)-2-(4-{[(6-bromopyridin-2-yl)methyl](methyl)carbamoyl}benzyl)-5-[(R)-{[tert-butyl(dimethyl)silyl]oxy}(phenyl)methyl]-pyrrolidine-1-carboxylate 
• 1093878-97-7 tert-butyl [(6-bromopyridin-2-yl)methyl]methylcarbamate 

Relevant articles and documents

INHIBITORS OF JANUS KINASES

The instant invention provides for compounds that inhibit the four known mammalian JAK kinases (JAK1, JAK2, JAK3 and TYK2) and PDK1. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting the activity of JAK1, JAK2, JAK3 TYK2 and PDK1 by administering the compound to a patient in need of treatment for myeloproliferative disorders or cancer.

PYRIDINE, PYRIMIDINE AND PYRAZINE DERIVATIVES AS GPCR AGONISTS

Compounds of formula (I): R1-A-V-B-R2 , wherein V is phenyl or a 6-membered heteroaryl ring containing up to three N-atoms, or pharmaceutically acceptable salts thereof, are agonists of GPR116 and are useful for the treatment of obesity, and for the treatment of diabetes.

Cognition enhancing derivatives of isoxazole triazoloindane GABA-A alpha 5 receptor subunit ligands

The present invention relates to compounds of formula I: in which R1 is a linear group or a five membered heterocycle optionally fused to a phenyl ring, R2 is a 5-membered heterocycle, R3 is chosen from a range of substituents, m is 0-3 and n is 0 or 1; the compounds are generally inverse agonists at GABA-A receptors containing the alpha 5 subunit and so are useful in methods of enhancing cognition in subjects with diminished cognition in diseases such as Alzheimer's Disease.