675124-91-1

Basic information

• Product Name: L-Leucine, 3-amino-, methyl ester, (3R)- (9CI)
• Synonyms: L-Leucine, 3-amino-, methyl ester, (3R)- (9CI)
• CAS NO: 675124-91-1
• Molecular Formula: C7H16N2O2
• Molecular Weight: 160.21414
• Product Categories: GLYCINESCAFFOLD
• Mol File: 675124-91-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: L-Leucine, 3-amino-, methyl ester, (3R)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: L-Leucine, 3-amino-, methyl ester, (3R)- (9CI)(675124-91-1)
• EPA Substance Registry System: L-Leucine, 3-amino-, methyl ester, (3R)- (9CI)(675124-91-1)

Safety Data

• Hazardous Substances Data: 675124-91-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
L-Leucine, 3-amino-, methyl ester, (3R)(9CI) is used as a building block for the synthesis of peptide and protein-based drugs due to its ability to contribute to the development of novel therapeutic agents.
Used in Nutrition and Fitness Industry:
L-Leucine, 3-amino-, methyl ester, (3R)(9CI) is used as a supplement to support muscle protein synthesis, making it a popular choice in the fitness and bodybuilding industry for enhancing athletic performance and muscle growth.

Upstream product

• 67-56-1 methanol 
• 134359-77-6 2,3-diamino-4-methylpentanoic acid 
• 675124-90-0 (+)-methyl [(2S,3R,Ss)-2-amino-4-methyl-3-(p-tolylsulfinylamino)]pentanoate 
• 596823-44-8 (+)-methyl [(2S,4S,5R,S_S)-2-phenyl-5-(i-propyl)-1-(p-tolylsulfinyl)-1,3-imidazolidin-4-yl]carboxylate 
• 134359-76-5 ethyl 2-amino-4-methyl-3-nitropentanoate 
• 39090-90-9 ethyl 4-methyl-3-nitro-2-pentenoate 

Relevant articles and documents

Fine-Tuned Aminal Cleavage: A Concise Route to Differentially Protected Enantiopure syn-α,β-Diamino Esters

A survey of routes for aminal cleavage of N-sulfinylimidazolidines has been carried out, and selective conditions to cleave the aminal moiety while preserving the sulfinamide group unaltered have been found. Thus, the treatment of enantiopure N-sulfinylimidazolidines with aqueous H3PO 4 in THF affords enantiopure N-sulfinyldiamino esters in excellent yields, while the presence of MeOH as cosolvent allows for the simultaneous removal of the sulfinamide group and aminal cleavage. The behavior of these substrates in a variety of chemical transformations has been explored.

Synthesis and Biological Activity of Angiotensin II Analogues Containing a Val-His Replacement, ValΨHis

The dipeptide mimic ValΨHis (4) was incorporated into angiotensin II (AII) analogues to provide an octapeptide saralisn derivative (29) as well as tetrapeptide analogue 19.Three C-terminal tetrapeptides (21, 25, and 28) were also prepared.All